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This motif also exists in all known structures of scorpion toxins, irrespective of their size, sequence, and function. Strikingly, antibacterial insect defensins also adopt this folding pattern.<\/jats:p>","DOI":"10.1126\/science.1720574","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T22:10:16Z","timestamp":1160086216000},"page":"1521-1523","source":"Crossref","is-referenced-by-count":298,"title":["Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins"],"prefix":"10.1126","volume":"254","author":[{"given":"Francois","family":"Bontems","sequence":"first","affiliation":[{"name":"D\u00e9partement d'Ing\u00e9nierie et d'Etudes des Prot\u00e9ines, Gif sur Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Roumestand","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'Ing\u00e9nierie et d'Etudes des Prot\u00e9ines, Gif sur Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Gilquin","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'Ing\u00e9nierie et d'Etudes des Prot\u00e9ines, Gif sur Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"M\u00e9nez","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'Ing\u00e9nierie et d'Etudes des Prot\u00e9ines, Gif sur Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Toma","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'Ing\u00e9nierie et d'Etudes des Prot\u00e9ines, Gif sur Yvette, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0014-5793(84)80014-9","volume":"165","year":"1984","unstructured":"ARSENIEV, A.S., NMR SOLUTION SPATIAL STRUCTURE OF SHORT SCORPION INSECTOTOXIN-I5A, FEBS LETTERS 165: 57 (1984).","journal-title":"FEBS LETTERS"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1432-1033.1991.tb15780.x","volume":"196","year":"1991","unstructured":"BONTEMS, F, 3-DIMENSIONAL STRUCTURE OF NATURAL CHARYBDOTOXIN IN AQUEOUS-SOLUTION BY H-1-NMR - CHARYBDOTOXIN POSSESSES A STRUCTURAL MOTIF FOUND IN OTHER SCORPION TOXINS, EUROPEAN JOURNAL OF BIOCHEMISTRY 196: 19 (1991).","journal-title":"EUROPEAN JOURNAL OF BIOCHEMISTRY"},{"key":"e_1_2_1_3_1","unstructured":"Brunger A. 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