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Injected intraperitoneally into mice, it inhibits splenomegaly and hepatomegaly induced by Friend leukemia virus and respiratory infections caused by influenza A\n            <jats:sub>0<\/jats:sub>\n            , A\n            <jats:sub>2<\/jats:sub>\n            , and B viruses and parainfluenza 1 virus. Oral or aerosol treatment of parainfluenza virus infections is also effective.\n          <\/jats:p>","DOI":"10.1126\/science.177.4050.705","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T14:03:38Z","timestamp":1160057018000},"page":"705-706","source":"Crossref","is-referenced-by-count":899,"title":["Broad-Spectrum Antiviral Activity of Virazole: 1-\u03b2-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide"],"prefix":"10.1126","volume":"177","author":[{"given":"Robert W.","family":"Sidwell","sequence":"first","affiliation":[{"name":"ICN Nucleic Acid Research Institute, Irvine, California 92664"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Huffman","sequence":"additional","affiliation":[{"name":"ICN Nucleic Acid Research Institute, Irvine, California 92664"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. 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