{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T07:05:33Z","timestamp":1777014333447,"version":"3.51.4"},"reference-count":21,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4085","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1973,5,4]]},"abstract":"<jats:p>\n            Contrary to general belief, larvae of\n            <jats:italic>Ancylostoma duodenale<\/jats:italic>\n            do not always develop directly to adulthood upon invasion of man. In West Bengal, India, arrested development appears to be a seasonal phenomenon which results in (i) reduction of egg output wasted in seeding an inhospitable environment and (ii) a marked increase in eggs entering the environment just before the monsoon begins.\n          <\/jats:p>","DOI":"10.1126\/science.180.4085.502","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T14:05:45Z","timestamp":1160057145000},"page":"502-504","source":"Crossref","is-referenced-by-count":84,"title":["Arrested Development in Human Hookworm Infections: An Adaptation to a Seasonally Unfavorable External Environment"],"prefix":"10.1126","volume":"180","author":[{"given":"G. A.","family":"Schad","sequence":"first","affiliation":[{"name":"Department of Pathobiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. B.","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Division of Parasitology, Calcutta School of Tropical Medicine, Calcutta 12, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. G.","family":"Dean","sequence":"additional","affiliation":[{"name":"Johns Hopkins University Center for Medical Research and Training, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. K.","family":"Kochar","sequence":"additional","affiliation":[{"name":"Johns Hopkins University Center for Medical Research and Training, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. A.","family":"Nawalinski","sequence":"additional","affiliation":[{"name":"Johns Hopkins University Center for Medical Research and Training, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Johns Hopkins University Center for Medical Research and Training, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Tonascia","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0034-5288(18)34440-0","volume":"10","year":"1969","unstructured":"ARMOUR, J, INHIBITION OF OSTERTAGIA OSTERTAGI AT EARLY FOURTH LARVAL STAGE .I. SEASONAL INCIDENCE, RESEARCH IN VETERINARY SCIENCE 10: 232 (1969).","journal-title":"RESEARCH IN VETERINARY SCIENCE"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0034-5288(18)34441-2","volume":"10","year":"1969","unstructured":"ARMOUR, J, INHIBITION OF OSTERTAGIA OSTERTAGI AT EARLY FOURTH LARVAL STAGE .2. INFLUENCE OF ENVIRONMENT ON HOST OR PARASITE, RESEARCH IN VETERINARY SCIENCE 10: 238 (1969).","journal-title":"RESEARCH IN VETERINARY SCIENCE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/vr.86.7.184","volume":"86","year":"1970","unstructured":"ARMOUR, J, BOVINE OSTERTAGIASIS . A REVIEW, VETERINARY RECORD 86: 184 (1970).","journal-title":"VETERINARY RECORD"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4269\/ajtmh.1953.2.102","volume":"2","year":"1953","unstructured":"BEAVER, P.C., PERSISTENCE OF HOOKWORM LARVAE IN SOIL, AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 2: 102 (1953).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0020-7519(72)90028-8","volume":"2","year":"1972","unstructured":"BLITZ, N.M., INT J PARASITOL 2: 5 (1972).","journal-title":"INT J PARASITOL"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0020-7519(72)90029-X","volume":"2","year":"1972","unstructured":"BLITZ, N.M., INT J PARASITOL 2: 13 (1972).","journal-title":"INT J PARASITOL"},{"key":"e_1_2_1_7_1","first-page":"1064","volume":"147","year":"1953","unstructured":"BRUMPT, L.C., *DIAPAUSE DES ANKYLOSTOMES CHEZ LES GRANDS ANEMIQUES, COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES 147: 1064 (1953).","journal-title":"COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES"},{"key":"e_1_2_1_8_1","first-page":"357","volume":"15","year":"1935","unstructured":"CHANDLER, A.C., AMERICAN JOURNAL OF TROPICAL MEDICINE 15: 357 (1935).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE"},{"key":"e_1_2_1_9_1","first-page":"146","year":"1929","unstructured":"Chandler, A. C., Hookworm Disease: 146 (1929).","journal-title":"Hookworm Disease"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1017\/S0022149X00032600","volume":"26","year":"1952","unstructured":"HUNTER, G.C., J HELMINTHOL 26: 157 (1952).","journal-title":"J HELMINTHOL"},{"key":"e_1_2_1_11_1","first-page":"363","volume":"14","year":"1934","unstructured":"KENDRICK, J.F., AMERICAN JOURNAL OF TROPICAL MEDICINE 14: 363 (1934).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1017\/S0022149X00022422","volume":"36","year":"1962","unstructured":"MADSEN, H, J HELMINTHOL 36: 143 (1962).","journal-title":"J HELMINTHOL"},{"key":"e_1_2_1_13_1","first-page":"685","volume":"18","year":"1930","unstructured":"MAPLESTONE, P.A., INDIAN JOURNAL OF MEDICAL RESEARCH 18: 685 (1930).","journal-title":"INDIAN JOURNAL OF MEDICAL RESEARCH"},{"key":"e_1_2_1_14_1","first-page":"1145","volume":"19","year":"1932","unstructured":"MAPLESTONE, P.A., INDIAN JOURNAL OF MEDICAL RESEARCH 19: 1145 (1932).","journal-title":"INDIAN JOURNAL OF MEDICAL RESEARCH"},{"key":"e_1_2_1_15_1","first-page":"383","volume":"17","year":"1968","unstructured":"MARTIN, L. K., AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 17: 383 (1968).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_16_1","first-page":"35","volume":"126","year":"1970","unstructured":"MICHEL, J.F., BR VET J 126: 35 (1970).","journal-title":"BR VET J"},{"key":"e_1_2_1_17_1","first-page":"67","year":"1968","unstructured":"Michel, J. F., Immunity to Parasites: 67 (1968).","journal-title":"Immunity to Parasites"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.4269\/ajtmh.1966.15.1032","volume":"15","year":"1966","unstructured":"ROCHE, M, AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 15: 1032 (1966).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1136\/vr.86.6.176","volume":"86","year":"1970","unstructured":"STOCKDALE, PHG, AGE OF INFECTIVE LARVAE . A CONTRIBUTORY FACTOR IN INHIBITION OF DEVELOPMENT OF OBELISCOIDES CUNICULI IN RABBITS, VETERINARY RECORD 86: 176 (1970).","journal-title":"VETERINARY RECORD"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1749-6632.1962.tb30592.x","volume":"98","year":"1962","unstructured":"STOLL, N.R., FOR HOOKWORM DIAGNOSIS, IS FINDING AN EGG ENOUGH, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 98: 712 (1962).","journal-title":"ANNALS OF THE NEW YORK ACADEMY OF SCIENCES"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/jid.1967.129","volume":"49","year":"1967","unstructured":"STONE, O.J., CUTANEOUS HOOKWORM RESERVOIR, JOURNAL OF INVESTIGATIVE DERMATOLOGY 49: 237 (1967).","journal-title":"JOURNAL OF INVESTIGATIVE DERMATOLOGY"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.180.4085.502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T21:05:40Z","timestamp":1705007140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.180.4085.502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,5,4]]},"references-count":21,"journal-issue":{"issue":"4085","published-print":{"date-parts":[[1973,5,4]]}},"alternative-id":["10.1126\/science.180.4085.502"],"URL":"https:\/\/doi.org\/10.1126\/science.180.4085.502","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,5,4]]}}}