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Utilization of palmitate by isolated mitochondria was more impaired than utilization of palmitylcarnitine, suggesting a more severe defect of carnitine palmityltransferase I than transferase II. Thus, myoglobinuria may be due to a genetic defect of lipid metabolism in skeletal muscle.<\/jats:p>","DOI":"10.1126\/science.182.4115.929","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T14:05:45Z","timestamp":1160057145000},"page":"929-931","source":"Crossref","is-referenced-by-count":397,"title":["Muscle Carnitine Palmityltransferase Deficiency and Myoglobinuria"],"prefix":"10.1126","volume":"182","author":[{"given":"Salvatore","family":"DiMauro","sequence":"first","affiliation":[{"name":"Department of Neurology and Clinical Research Center, University of Pennsylvania, Philadelphia 19174"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola M. 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