{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:00:42Z","timestamp":1761742842001},"reference-count":26,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4122","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1974,1,25]]},"abstract":"<jats:p>In intracellular parasitism the host cell is a true and hospitable host. The parasite does not have to break in the door. It has subtle ways of inducing the host to open the door and welcome it in. One of the exciting fields in the future of parasitology is to find out what these ways are and why they are sometimes so highly specific that the cell that invites one parasite in will not open the door to another closely related species. Once inside, the parasite not only exploits nutrients already available in the cell, and the cell's energy-yielding system, but it further induces the cell to assist actively in its nutrition. Like a bandit who has cajoled his way in, the parasite now forces his host to prepare a banquet for him. Finally it may destroy its host cell, as in most of the associations I have described herein, or it may stimulate its host cell to abnormal increase in size or to have an altered metabolism with the formation of new products. Or it may even contribute some positive benefit to the host cell or to the multicellular organism of which the cell is a part, so that the two kinds of organisms then live together in a state of mutualism or symbiosis.<\/jats:p>","DOI":"10.1126\/science.183.4122.269","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T15:10:48Z","timestamp":1160061048000},"page":"269-273","source":"Crossref","is-referenced-by-count":37,"title":["Some Aspects of Intracellular Parasitism"],"prefix":"10.1126","volume":"183","author":[{"given":"William","family":"Trager","sequence":"first","affiliation":[{"name":"Rockefeller University, New York 10021"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/j.1550-7408.1967.tb01985.x","volume":"14","year":"1967","unstructured":"BENNETT, T.P., PANTOTHENIC ACID METABOLISM DURING AVIAN MALARIA INFECTION - PANTOTHENATE KINASE ACTIVITY IN DUCK ERYTHROCYTES AND IN PLASMODIUM LOPHURAE, JOURNAL OF PROTOZOOLOGY 14: 214 (1967).","journal-title":"JOURNAL OF PROTOZOOLOGY"},{"key":"e_1_2_1_2_1","first-page":"450","volume":"20","year":"1969","unstructured":"BROMMER, W, ZEITSCHRIFT FUR TROPENMEDIZIN UND PARASITOLOGIE 20: 450 (1969).","journal-title":"ZEITSCHRIFT FUR TROPENMEDIZIN UND PARASITOLOGIE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.167.3919.893"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.1550-7408.1967.tb02061.x","volume":"14","year":"1967","unstructured":"HAMMOND, D.M., FINE STRUCTURES ASSOCIATED WITH NUTRITION OF INTRACELLULAR PARASITE EIMERIA AUBURNENSIS, JOURNAL OF PROTOZOOLOGY 14: 678 (1967).","journal-title":"JOURNAL OF PROTOZOOLOGY"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0021-9258(18)63238-7","volume":"245","year":"1970","unstructured":"HENDERSON, PJF, BONGKREKIC ACID - AN INHIBITOR OF ADENINE NUCLEOTIDE TRANSLOCASE OF MITOCHONDRIA, JOURNAL OF BIOLOGICAL CHEMISTRY 245: 1319 (1970).","journal-title":"JOURNAL OF BIOLOGICAL CHEMISTRY"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.2307\/3277307","volume":"55","year":"1969","unstructured":"HERMAN, R, OSMOTIC FRAGILITY OF NORMAL DUCK ERYTHROCYTES AS INFLUENCED BY EXTRACTS OF PLASMODIUM LOPHURAE P LOPHURAE-INFECTED CELLS, AND PLASMA, JOURNAL OF PARASITOLOGY 55: 626 (1969).","journal-title":"JOURNAL OF PARASITOLOGY"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0022-2011(68)90323-6","volume":"12","year":"1968","unstructured":"ISHIHARA, R, SOME OBSERVATIONS ON FINE STRUCTURE OF SPOROPLASM DISCHARGED FROM SPORES OF A MICROSPORIDIAN NOSEMA BOMBYCIS, JOURNAL OF INVERTEBRATE PATHOLOGY 12: 245 (1968).","journal-title":"JOURNAL OF INVERTEBRATE PATHOLOGY"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1084\/jem.136.5.1173","volume":"136","year":"1972","unstructured":"JONES, T.C., INTERACTION BETWEEN TOXOPLASMA-GONDII AND MAMMALIAN-CELLS .2. 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