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A defect in cyclic GMP metabolism may be characteristic of early-onset degenerative diseases of the retina, possibly including those that affect humans.<\/jats:p>","DOI":"10.1126\/science.210508","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T16:35:25Z","timestamp":1160066125000},"page":"1133-1134","source":"Crossref","is-referenced-by-count":165,"title":["Rod-Cone Dysplasia in Irish Setters: A Defect in Cyclic GMP Metabolism in Visual Cells"],"prefix":"10.1126","volume":"201","author":[{"given":"G.","family":"Aquirre","sequence":"first","affiliation":[{"name":"Section of Ophthalmology, School of Veterinary Medicine, University of Pennsylvania. Philadelphia 19104"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Farber","sequence":"additional","affiliation":[{"name":"Jules Stein Eye Institute, School of Medicine. 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