{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T00:11:22Z","timestamp":1705104682146},"reference-count":1,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5239","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1995,11,17]]},"abstract":"<jats:p>Minneapolis\u2014Participants in the 45th Annual Meeting of the American Society for Human Genetics learned about the possible solution of another genetic mystery: how a defect in a single gene might bring about the many symptoms of myotonic dystrophy (DM). The RNA produced by the mutant DM gene somehow interferes with the cell's handling of RNAs made by other genes, giving it the potential to expand its reach into several different systems. Researchers also reported tracing the origin of the \u201csporadic\u201d mutations that cause Apert's syndrome to the patients' fathers. That's no surprise, but the method they used has the potential to help identify the origins of other sporadic genetic disorders.<\/jats:p>","DOI":"10.1126\/science.270.5239.1120","type":"journal-article","created":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T18:19:42Z","timestamp":1161973182000},"page":"1120-1121","source":"Crossref","is-referenced-by-count":3,"title":["Annual Genetics Meeting: Some Puzzles, Some Answers"],"prefix":"10.1126","volume":"270","author":[{"given":"Rachel","family":"Nowak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_2_2","first-page":"1135","volume":"268","author":"JOHNSON K","year":"1995","unstructured":"JOHNSON K, SCIENCE 268, 1135 (1995).","journal-title":"SCIENCE"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.270.5239.1120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T21:16:04Z","timestamp":1705094164000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.270.5239.1120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11,17]]},"references-count":1,"journal-issue":{"issue":"5239","published-print":{"date-parts":[[1995,11,17]]}},"alternative-id":["10.1126\/science.270.5239.1120"],"URL":"https:\/\/doi.org\/10.1126\/science.270.5239.1120","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11,17]]}}}