{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T00:07:24Z","timestamp":1705190844338},"reference-count":0,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5274","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1996,7,26]]},"abstract":"<jats:p>\n            Two groups of researchers, one of which reports its results on\n            <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"494\" related-article-type=\"in-this-issue\" vol=\"273\" xlink:href=\"10.1126\/science.273.5274.494\" xlink:type=\"simple\">page 494<\/jats:related-article>\n            , have found a way to tag chromosomes with fluorescent markers so that each chromosome can be depicted by a computer as having a distinctive color. The techniques are likely to be useful for detecting chromosomal rearrangements and other abnormalities in cancer cells, and in screening for defects that underlie genetic disorders such as Down syndrome.\n          <\/jats:p>","DOI":"10.1126\/science.273.5274.430","type":"journal-article","created":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T18:30:41Z","timestamp":1161973841000},"page":"430-430","source":"Crossref","is-referenced-by-count":4,"title":["New Methods for Expanding the Chromosomal Paint Kit"],"prefix":"10.1126","volume":"273","author":[{"given":"Jean","family":"Marx","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.273.5274.430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T04:15:27Z","timestamp":1705119327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.273.5274.430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7,26]]},"references-count":0,"journal-issue":{"issue":"5274","published-print":{"date-parts":[[1996,7,26]]}},"alternative-id":["10.1126\/science.273.5274.430"],"URL":"https:\/\/doi.org\/10.1126\/science.273.5274.430","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7,26]]}}}