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This animal model reproduced key aspects of human EBV infection, including oral transmission, atypical lymphocytosis, lymphadenopathy, activation of CD23\n            <jats:sup>+<\/jats:sup>\n            peripheral blood B cells, sustained serologic responses to lytic and latent EBV antigens, latent infection in the peripheral blood, and virus persistence in oropharyngeal secretions. This system may be useful for studying the pathogenesis, prevention, and treatment of EBV infection and associated oncogenesis.\n          <\/jats:p>","DOI":"10.1126\/science.276.5321.2030","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:37:56Z","timestamp":1027762676000},"page":"2030-2033","source":"Crossref","is-referenced-by-count":166,"title":["An Animal Model for Acute and Persistent Epstein-Barr Virus Infection"],"prefix":"10.1126","volume":"276","author":[{"given":"Amir","family":"Moghaddam","sequence":"first","affiliation":[{"name":"A. Moghaddam, B. 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