{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:41:12Z","timestamp":1779180072676,"version":"3.51.4"},"reference-count":12,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5845","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2007,9,21]]},"DOI":"10.1126\/science.317.5845.1680","type":"journal-article","created":{"date-parts":[[2007,9,20]],"date-time":"2007-09-20T21:24:10Z","timestamp":1190323450000},"page":"1680-1680","source":"Crossref","is-referenced-by-count":17,"title":["Ethics and Refinement in Animal Research"],"prefix":"10.1126","volume":"317","author":[{"given":"I. 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Maynard C. Kosinski E. Diguet D. Emerich and H. H. Phuc Nguyen who provided information on clinical signs in different models; and P. Robinson who commented on a previous version of the Letter. Preparation of this Letter was part of the interdisciplinary project Comparative Genomics of Man and Pig funded by the Danish Agency for Science Technology and Innovation."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/full\/10.1126\/science.317.5845.1680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T21:39:39Z","timestamp":1705181979000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.317.5845.1680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,21]]},"references-count":12,"journal-issue":{"issue":"5845","published-print":{"date-parts":[[2007,9,21]]}},"alternative-id":["10.1126\/science.317.5845.1680"],"URL":"https:\/\/doi.org\/10.1126\/science.317.5845.1680","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,21]]}}}