{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:35:11Z","timestamp":1791106511542,"version":"4.1.0"},"reference-count":86,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4879","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1988,11,4]]},"abstract":"<jats:p>The cellular cues that guide neuronal growth cones toward their targets are highly conserved in such diverse organisms as insects and vertebrates. Evidence presented here suggests that the molecular mechanisms underlying these events may be equally conserved. This article describes the structure and function of fasciclin II, a glycoprotein expressed on a subset of fasciculating axons in the grasshopper embryo. Antibody perturbation experiments suggest that fasciclin II functions in mediating one form of neuronal recognition: selective fasciculation. Fasciclin II is a member of the immunoglobulin gene superfamily and is homologous in structure and function to the neural cell adhesion molecule N-CAM and to several other vertebrate cell adhesion molecules.<\/jats:p>","DOI":"10.1126\/science.3187519","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T21:21:15Z","timestamp":1160083275000},"page":"700-708","source":"Crossref","is-referenced-by-count":341,"title":["Growth Cone Guidance in Insects: Fasciclin II Is a Member of the Immunoglobulin Superfamily"],"prefix":"10.1126","volume":"242","author":[{"given":"Allan L.","family":"Harrelson","sequence":"first","affiliation":[{"name":"Howard Hughes Medical Institute and Department of Biochemistry, University of California, Berkeley 94720."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey S.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute and Department of Biochemistry, University of California, Berkeley 94720."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"1","volume":"83","year":"1986","unstructured":"ARQUINT, M, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 1 (1986).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1523\/JNEUROSCI.05-07-01808.1985","volume":"5","year":"1985","unstructured":"BALL, E.E., DEVELOPMENT OF NEUROMUSCULAR SPECIFICITY IN THE GRASSHOPPER EMBRYO - GUIDANCE OF MOTONEURON GROWTH CONES BY MUSCLE PIONEERS, JOURNAL OF NEUROSCIENCE 5: 1808 (1985).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/j.1460-2075.1987.tb04837.x","volume":"6","year":"1987","unstructured":"BARTHELS, D, ISOLATION AND NUCLEOTIDE-SEQUENCE OF MOUSE NCAM CDNA THAT CODES FOR A MR 79000 POLYPEPTIDE WITHOUT A MEMBRANE-SPANNING REGION, EMBO JOURNAL 6: 907 (1987).","journal-title":"EMBO JOURNAL"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1242\/jeb.112.1.45","volume":"112","year":"1984","unstructured":"BASTIANI, M, FROM EMBRYONIC FASCICLES TO ADULT TRACTS - ORGANIZATION OF NEUROPIL FROM A DEVELOPMENTAL PERSPECTIVE, JOURNAL OF EXPERIMENTAL BIOLOGY 112: 45 (1984).","journal-title":"JOURNAL OF EXPERIMENTAL BIOLOGY"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/0092-8674(87)90072-9","volume":"48","year":"1987","unstructured":"BASTIANI, M.J., EXPRESSION OF FASCICLIN-I AND FASCICLIN-II GLYCOPROTEINS ON SUBSETS OF AXON PATHWAYS DURING NEURONAL DEVELOPMENT IN THE GRASSHOPPER, CELL 48: 745 (1987).","journal-title":"CELL"},{"key":"e_1_2_1_6_1","first-page":"63","year":"1984","unstructured":"BASTIANI, M.J., CELLULAR MOL APPROAC: 63 (1984).","journal-title":"CELLULAR MOL APPROAC"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1523\/JNEUROSCI.04-09-02311.1984","volume":"4","year":"1984","unstructured":"BASTIANI, M.J., PATHFINDING BY NEURONAL GROWTH CONES IN GRASSHOPPER EMBRYOS .3. SELECTIVE AFFINITY OF THE G-GROWTH CONE FOR THE P-CELLS WITHIN THE A\/P FASCICLE, JOURNAL OF NEUROSCIENCE 4: 2311 (1984).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1523\/JNEUROSCI.06-12-03518.1986","volume":"6","year":"1986","unstructured":"BASTIANI, M.J., GUIDANCE OF NEURONAL GROWTH CONES IN THE GRASSHOPPER EMBRYO .1. RECOGNITION OF A SPECIFIC AXONAL PATHWAY BY THE PCC NEURON, JOURNAL OF NEUROSCIENCE 6: 3518 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"3542","DOI":"10.1523\/JNEUROSCI.06-12-03542.1986","volume":"6","year":"1986","unstructured":"BASTIANI, M.J., GUIDANCE OF NEURONAL GROWTH CONES IN THE GRASSHOPPER EMBRYO .3. RECOGNITION OF SPECIFIC GLIAL PATHWAYS, JOURNAL OF NEUROSCIENCE 6: 3542 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_10_1","first-page":"1849","volume":"81","year":"1984","unstructured":"BASTIANI, M.J., NEURONAL GROWTH CONES - SPECIFIC INTERACTIONS MEDIATED BY FILOPODIAL INSERTION AND INDUCTION OF COATED VESICLES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 1849 (1984).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0166-2236(85)90099-2","volume":"8","year":"1985","unstructured":"BASTIANI, M.J., NEURONAL SPECIFICITY AND GROWTH CONE GUIDANCE IN GRASSHOPPER AND DROSOPHILA EMBRYOS, TRENDS IN NEUROSCIENCES 8: 257 (1985).","journal-title":"TRENDS IN NEUROSCIENCES"},{"key":"e_1_2_1_12_1","first-page":"317","volume":"61","year":"1981","unstructured":"BATE, C.M., EMBRYOGENESIS OF AN INSECT NERVOUS-SYSTEM .2. A 2ND CLASS OF NEURON PRECURSOR CELLS AND THE ORIGIN OF THE INTERSEGMENTAL CONNECTIVES, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 61: 317 (1981).","journal-title":"JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY"},{"key":"e_1_2_1_13_1","first-page":"107","volume":"35","year":"1976","unstructured":"BATE, C.M., EMBRYOGENESIS OF AN INSECT NERVOUS-SYSTEM .1. MAP OF THORACIC AND ABDOMINAL NEUROBLASTS IN LOCUSTA-MIGRATORIA, JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY 35: 107 (1976).","journal-title":"JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1083\/jcb.107.1.353","volume":"107","year":"1988","unstructured":"BIXBY, J.L., IDENTIFICATION OF THE MAJOR PROTEINS THAT PROMOTE NEURONAL PROCESS OUTGROWTH ON SCHWANN-CELLS INVITRO, JOURNAL OF CELL BIOLOGY 107: 353 (1988).","journal-title":"JOURNAL OF CELL BIOLOGY"},{"key":"e_1_2_1_15_1","first-page":"2555","volume":"84","year":"1987","unstructured":"BIXBY, J.L., NEURITE OUTGROWTH ON MUSCLE-CELL SURFACES INVOLVES EXTRACELLULAR-MATRIX RECEPTORS AS WELL AS CA-2+-DEPENDENT AND CA-2+-INDEPENDENT CELL-ADHESION MOLECULES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84: 2555 (1987).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"4165","DOI":"10.1523\/JNEUROSCI.07-12-04165.1987","volume":"7","year":"1987","unstructured":"BLAIR, S.S., THE GUIDANCE OF AXONS FROM TRANSPLANTED NEURONS THROUGH ANEURAL DROSOPHILA WINGS, JOURNAL OF NEUROSCIENCE 7: 4165 (1987).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0166-2236(85)90103-1","volume":"8","year":"1985","unstructured":"BLAIR, S.S., AXON GUIDANCE IN THE WING OF DROSOPHILA, TRENDS IN NEUROSCIENCES 8: 284 (1985).","journal-title":"TRENDS IN NEUROSCIENCES"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00402027","volume":"196","year":"1987","unstructured":"BODMER, R, MORPHOLOGICAL-DIFFERENTIATION OF THE EMBRYONIC PERIPHERAL NEURONS IN DROSOPHILA, ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY 196: 69 (1987).","journal-title":"ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0092-8674(87)90580-0","volume":"51","year":"1987","unstructured":"BOGAERT, T, THE DROSOPHILA PS2 ANTIGEN IS AN INVERTEBRATE INTEGRIN THAT, LIKE THE FIBRONECTIN RECEPTOR, BECOMES LOCALIZED TO MUSCLE ATTACHMENTS, CELL 51: 929 (1987).","journal-title":"CELL"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1083\/jcb.106.4.1281","volume":"106","year":"1988","unstructured":"CARONI, P, 2 MEMBRANE-PROTEIN FRACTIONS FROM RAT CENTRAL MYELIN WITH INHIBITORY PROPERTIES FOR NEURITE GROWTH AND FIBROBLAST SPREADING, JOURNAL OF CELL BIOLOGY 106: 1281 (1988).","journal-title":"JOURNAL OF CELL BIOLOGY"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0896-6273(88)90212-7","volume":"1","year":"1988","unstructured":"CARONI, P, ANTIBODY AGAINST MYELIN-ASSOCIATED INHIBITOR OF NEURITE GROWTH NEUTRALIZES NONPERMISSIVE SUBSTRATE PROPERTIES OF CNS WHITE MATTER, NEURON 1: 85 (1988).","journal-title":"NEURON"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1523\/JNEUROSCI.06-02-00364.1986","volume":"6","year":"1986","unstructured":"CAUDY, M, PIONEER GROWTH CONE MORPHOLOGIES REVEAL PROXIMAL INCREASES IN SUBSTRATE AFFINITY WITHIN LEG SEGMENTS OF GRASSHOPPER EMBRYOS, JOURNAL OF NEUROSCIENCE 6: 364 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1523\/JNEUROSCI.06-06-01781.1986","volume":"6","year":"1986","unstructured":"CAUDY, M, PIONEER GROWTH CONE STEERING ALONG A SERIES OF NEURONAL AND NONNEURONAL CUES OF DIFFERENT AFFINITIES, JOURNAL OF NEUROSCIENCE 6: 1781 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1083\/jcb.104.2.355","volume":"104","year":"1987","unstructured":"CHANG, S, EXTENSION OF NEURITES ON AXONS IS IMPAIRED BY ANTIBODIES AGAINST SPECIFIC NEURAL CELL-SURFACE GLYCOPROTEINS, JOURNAL OF CELL BIOLOGY 104: 355 (1987).","journal-title":"JOURNAL OF CELL BIOLOGY"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3363372"},{"key":"e_1_2_1_26_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0092-8674(88)90538-7","volume":"52","year":"1988","unstructured":"CREWS, S.T., THE DROSOPHILA SINGLE-MINDED GENE ENCODES A NUCLEAR-PROTEIN WITH SEQUENCE SIMILARITY TO THE PER GENE-PRODUCT, CELL 52: 143 (1988).","journal-title":"CELL"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3576199"},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0076-6879(83)91049-2","volume":"91","year":"1983","unstructured":"DAYHOFF, M.O., ESTABLISHING HOMOLOGIES IN PROTEIN SEQUENCES, METHODS IN ENZYMOLOGY 91: 524 (1983).","journal-title":"METHODS IN ENZYMOLOGY"},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0896-6273(88)90194-8","volume":"1","year":"1988","unstructured":"DODD, J, SPATIAL REGULATION OF AXONAL GLYCOPROTEIN EXPRESSION ON SUBSETS OF EMBRYONIC SPINAL NEURONS, NEURON 1: 105 (1988).","journal-title":"NEURON"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3055291"},{"key":"e_1_2_1_31_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0012-1606(85)90445-2","volume":"111","year":"1985","unstructured":"DOE, C.Q., EARLY EVENTS IN INSECT NEUROGENESIS .1. DEVELOPMENT AND SEGMENTAL DIFFERENCES IN THE PATTERN OF NEURONAL PRECURSOR CELLS, DEVELOPMENTAL BIOLOGY 111: 193 (1985).","journal-title":"DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_32_1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0012-1606(85)90446-4","volume":"111","year":"1985","unstructured":"DOE, C.Q., EARLY EVENTS IN INSECT NEUROGENESIS .2. THE ROLE OF CELL-INTERACTIONS AND CELL LINEAGE IN THE DETERMINATION OF NEURONAL PRECURSOR CELLS, DEVELOPMENTAL BIOLOGY 111: 206 (1985).","journal-title":"DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_33_1","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1523\/JNEUROSCI.06-12-03552.1986","volume":"6","year":"1986","unstructured":"DOE, C.Q., GUIDANCE OF NEURONAL GROWTH CONES IN THE GRASSHOPPER EMBRYO .4. TEMPORAL DELAY EXPERIMENTS, JOURNAL OF NEUROSCIENCE 6: 3552 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_34_1","first-page":"67","volume":"312","year":"1985","unstructured":"DOE, C.Q., FROM EPITHELIUM TO NEUROBLASTS TO NEURONS - THE ROLE OF CELL-INTERACTIONS AND CELL LINEAGE DURING INSECT NEUROGENESIS, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 312: 67 (1985).","journal-title":"PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES"},{"key":"e_1_2_1_35_1","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.1523\/JNEUROSCI.06-12-03532.1986","volume":"6","year":"1986","unstructured":"DULAC, S, GUIDANCE OF NEURONAL GROWTH CONES IN THE GRASSHOPPER EMBRYO .2. RECOGNITION OF A SPECIFIC AXONAL PATHWAY BY THE ACC NEURON, JOURNAL OF NEUROSCIENCE 6: 3532 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1984.tb01997.x"},{"key":"e_1_2_1_37_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF00376060","volume":"195","year":"1986","unstructured":"GHYSEN, A, SENSORY NEURONS AND PERIPHERAL PATHWAYS IN DROSOPHILA EMBRYOS, ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY 195: 281 (1986).","journal-title":"ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_38_1","first-page":"275","volume":"40","year":"1982","unstructured":"GOODMAN, C.S., SYMPOSIUM OF THE SOCIETY FOR DEVELOPMENTAL BIOLOGY 40: 275 (1982).","journal-title":"SYMPOSIUM OF THE SOCIETY FOR DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6474176"},{"key":"e_1_2_1_40_1","first-page":"96","year":"1987","unstructured":"HARRELSON, A.L., FRONTIERS DEV NEUROB: 96 (1987).","journal-title":"FRONTIERS DEV NEUROB"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6093252"},{"key":"e_1_2_1_42_1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.cb.01.110185.000435","volume":"1","year":"1985","unstructured":"HYNES, R, MOLECULAR-BIOLOGY OF FIBRONECTIN, ANNUAL REVIEW OF CELL BIOLOGY 1: 67 (1985).","journal-title":"ANNUAL REVIEW OF CELL BIOLOGY"},{"key":"e_1_2_1_43_1","unstructured":"ISHII N COMMUNICATION."},{"key":"e_1_2_1_44_1","unstructured":"JACOBS J.R. unpublished data."},{"key":"e_1_2_1_45_1","first-page":"2700","volume":"79","year":"1982","unstructured":"JAN, L.Y., ANTIBODIES TO HORSERADISH-PEROXIDASE AS SPECIFIC NEURONAL MARKERS IN DROSOPHILA AND IN GRASSHOPPER EMBRYOS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79: 2700 (1982).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES"},{"key":"e_1_2_1_46_1","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1523\/JNEUROSCI.05-09-02453.1985","volume":"5","year":"1985","unstructured":"JAN, Y.N., FORMATION OF NEURONAL PATHWAYS IN THE IMAGINAL DISKS OF DROSOPHILA-MELANOGASTER, JOURNAL OF NEUROSCIENCE 5: 2453 (1985).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_47_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0896-6273(88)90204-8","volume":"1","year":"1988","unstructured":"JESSELL, T.M., ADHESION MOLECULES AND THE HIERARCHY OF NEURAL DEVELOPMENT, NEURON 1: 3 (1988).","journal-title":"NEURON"},{"key":"e_1_2_1_48_1","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1523\/JNEUROSCI.06-09-02527.1986","volume":"6","year":"1986","unstructured":"KAPFHAMMER, J.P., THE SELECTIVE-INHIBITION OF GROWTH CONE EXTENSION BY SPECIFIC NEURITES IN CULTURE, JOURNAL OF NEUROSCIENCE 6: 2527 (1986).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_49_1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1523\/JNEUROSCI.07-01-00201.1987","volume":"7","year":"1987","unstructured":"KAPFHAMMER, J.P., COLLAPSE OF GROWTH CONE STRUCTURE ON CONTACT WITH SPECIFIC NEURITES IN CULTURE, JOURNAL OF NEUROSCIENCE 7: 201 (1987).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3738507"},{"key":"e_1_2_1_51_1","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1083\/jcb.101.4.1351","volume":"101","year":"1985","unstructured":"LANDER, A.D., J CELL BIOL 101: 1351 (1985).","journal-title":"J CELL BIOL"},{"key":"e_1_2_1_52_1","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/j.1460-2075.1987.tb04856.x","volume":"6","year":"1987","unstructured":"LEPTIN, M, DROSOPHILA POSITION-SPECIFIC ANTIGENS RESEMBLE THE VERTEBRATE FIBRONECTIN-RECEPTOR FAMILY, EMBO JOURNAL 6: 1037 (1987).","journal-title":"EMBO JOURNAL"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2983426"},{"key":"e_1_2_1_54_1","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/323538a0","volume":"323","year":"1986","unstructured":"LUMSDEN, AGS, CHEMOTROPIC EFFECT OF SPECIFIC TARGET EPITHELIUM IN THE DEVELOPING MAMMALIAN NERVOUS-SYSTEM, NATURE 323: 538 (1986).","journal-title":"NATURE"},{"key":"e_1_2_1_55_1","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1523\/JNEUROSCI.03-09-01746.1983","volume":"3","year":"1983","unstructured":"MACAGNO, E.R., THE EXPRESSION OF ANTIGENS BY EMBRYONIC NEURONS AND GLIA IN SEGMENTAL GANGLIA OF THE LEECH HAEMOPIS-MARMORATA, JOURNAL OF NEUROSCIENCE 3: 1746 (1983).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6356361"},{"key":"e_1_2_1_57_1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0092-8674(88)90166-3","volume":"53","year":"1988","unstructured":"MONTELL, D.J., DROSOPHILA SUBSTRATE ADHESION MOLECULE - SEQUENCE OF LAMININ-B1 CHAIN REVEALS DOMAINS OF HOMOLOGY WITH MOUSE, CELL 53: 463 (1988).","journal-title":"CELL"},{"key":"e_1_2_1_58_1","unstructured":"MONTELL D.J. unpublished data."},{"key":"e_1_2_1_59_1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/334701a0","volume":"334","year":"1988","unstructured":"MOOS, M, NEURAL ADHESION MOLECULE L1 AS A MEMBER OF THE IMMUNOGLOBULIN SUPERFAMILY WITH BINDING DOMAINS SIMILAR TO FIBRONECTIN, NATURE 334: 701 (1988).","journal-title":"NATURE"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6729457"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0012-1606(83)90015-5","volume":"95","year":"1983","unstructured":"NARDI, J.B., NEURONAL PATHFINDING IN DEVELOPING WINGS OF THE MOTH MANDUCA-SEXTA, DEVELOPMENTAL BIOLOGY 95: 163 (1983).","journal-title":"DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_62_1","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/0092-8674(87)90706-9","volume":"48","year":"1987","unstructured":"PATEL, N.H., CHARACTERIZATION AND CLONING OF FASCICLIN-III - A GLYCOPROTEIN EXPRESSED ON A SUBSET OF NEURONS AND AXON PATHWAYS IN DROSOPHILA, CELL 48: 975 (1987).","journal-title":"CELL"},{"key":"e_1_2_1_63_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0896-6273(88)90074-8","volume":"1","year":"1988","unstructured":"PATTERSON, P.H., ON THE IMPORTANCE OF BEING INHIBITED, OR SAYING NO TO GROWTH CONES, NEURON 1: 263 (1988).","journal-title":"NEURON"},{"key":"e_1_2_1_64_1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1101\/SQB.1983.048.01.063","volume":"48","year":"1983","unstructured":"RAPER, J.A., GUIDANCE OF NEURONAL GROWTH CONES - SELECTIVE FASCICULATION IN THE GRASSHOPPER EMBRYO, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 48: 587 (1983).","journal-title":"COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY"},{"key":"e_1_2_1_65_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1523\/JNEUROSCI.03-01-00020.1983","volume":"3","year":"1983","unstructured":"RAPER, J.A., PATHFINDING BY NEURONAL GROWTH CONES IN GRASSHOPPER EMBRYOS .1. DIVERGENT CHOICES MADE BY THE GROWTH CONES OF SIBLING NEURONS, JOURNAL OF NEUROSCIENCE 3: 20 (1983).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_66_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1523\/JNEUROSCI.03-01-00031.1983","volume":"3","year":"1983","unstructured":"RAPER, J.A., PATHFINDING BY NEURONAL GROWTH CONES IN GRASSHOPPER EMBRYOS .2. SELECTIVE FASCICULATION ONTO SPECIFIC AXONAL PATHWAYS, JOURNAL OF NEUROSCIENCE 3: 31 (1983).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_67_1","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1523\/JNEUROSCI.04-09-02329.1984","volume":"4","year":"1984","unstructured":"RAPER, J.A., PATHFINDING BY NEURONAL GROWTH CONES IN GRASSHOPPER EMBRYOS .4. THE EFFECTS OF ABLATING THE A-AXON AND P-AXON UPON THE BEHAVIOR OF THE G-GROWTH CONE, JOURNAL OF NEUROSCIENCE 4: 2329 (1984).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_68_1","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0092-8674(87)90107-3","volume":"51","year":"1987","unstructured":"RATHJEN, F.G., NEUROFASCIN - A NOVEL CHICK CELL-SURFACE GLYCOPROTEIN INVOLVED IN NEURITE-NEURITE INTERACTIONS, CELL 51: 841 (1987).","journal-title":"CELL"},{"key":"e_1_2_1_69_1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1083\/jcb.104.2.343","volume":"104","year":"1987","unstructured":"RATHJEN, F.G., MEMBRANE-GLYCOPROTEINS INVOLVED IN NEURITE FASCICULATION, JOURNAL OF CELL BIOLOGY 104: 343 (1987).","journal-title":"JOURNAL OF CELL BIOLOGY"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3131880"},{"key":"e_1_2_1_71_1","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1152\/physrev.1988.68.3.819","volume":"68","year":"1988","unstructured":"Rutishauser, U., Physiological Reviews 68: 819 (1988).","journal-title":"Physiological Reviews"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"e_1_2_1_73_1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0092-8674(88)90217-6","volume":"55","year":"1988","unstructured":"Seeger, M. A., Cell 55: 589 (1988).","journal-title":"Cell"},{"key":"e_1_2_1_74_1","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1523\/JNEUROSCI.07-12-04137.1987","volume":"7","year":"1987","unstructured":"SNOW, P.M., NEURAL-SPECIFIC CARBOHYDRATE MOIETY SHARED BY MANY SURFACE GLYCOPROTEINS IN DROSOPHILA AND GRASSHOPPER EMBRYOS, JOURNAL OF NEUROSCIENCE 7: 4137 (1987).","journal-title":"JOURNAL OF NEUROSCIENCE"},{"key":"e_1_2_1_75_1","first-page":"5291","volume":"85","year":"1988","unstructured":"SNOW, P.M., CHARACTERIZATION AND CLONING OF FASCICLIN-I AND FASCICLIN-II GLYCOPROTEINS IN THE GRASSHOPPER, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85: 5291 (1988).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_76_1","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/0092-8674(87)90180-2","volume":"50","year":"1987","unstructured":"STELLER, H, DISCONNECTED - A LOCUS REQUIRED FOR NEURONAL PATHWAY FORMATION IN THE VISUAL-SYSTEM OF DROSOPHILA, CELL 50: 1139 (1987).","journal-title":"CELL"},{"key":"e_1_2_1_77_1","unstructured":"TAGHERT P.H. COMMUNICATION."},{"key":"e_1_2_1_78_1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0012-1606(82)90356-6","volume":"94","year":"1982","unstructured":"TAGHERT, P.H., GUIDANCE OF PIONEER GROWTH CONES - FILOPODIAL CONTACTS AND COUPLING REVEALED WITH AN ANTIBODY TO LUCIFER YELLOW, DEVELOPMENTAL BIOLOGY 94: 391 (1982).","journal-title":"DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_79_1","first-page":"143","year":"1986","unstructured":"TAGHERT, P.H., INSECT NEUROCHEMISTR: 143 (1986).","journal-title":"INSECT NEUROCHEMISTR"},{"key":"e_1_2_1_80_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0092-8674(88)90537-5","volume":"52","year":"1988","unstructured":"THOMAS, J.B., MOLECULAR-GENETICS OF THE SINGLE-MINDED LOCUS - A GENE INVOLVED IN THE DEVELOPMENT OF THE DROSOPHILA NERVOUS-SYSTEM, CELL 52: 133 (1988).","journal-title":"CELL"},{"key":"e_1_2_1_81_1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/310203a0","volume":"310","year":"1984","unstructured":"THOMAS, J.B., FROM GRASSHOPPER TO DROSOPHILA - A COMMON PLAN FOR NEURONAL DEVELOPMENT, NATURE 310: 203 (1984).","journal-title":"NATURE"},{"key":"e_1_2_1_82_1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0896-6273(88)90207-3","volume":"1","year":"1988","unstructured":"TOMASELLI, K.J., N-CADHERIN AND INTEGRINS - 2 RECEPTOR SYSTEMS THAT MEDIATE NEURONAL PROCESS OUTGROWTH ON ASTROCYTE SURFACES, NEURON 1: 33 (1988).","journal-title":"NEURON"},{"key":"e_1_2_1_83_1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0012-1606(82)90252-4","volume":"93","year":"1982","unstructured":"WHITINGTON, P.M., AXON GROWTH FROM LIMB MOTO-NEURONS IN THE LOCUST EMBRYO - THE EFFECT OF TARGET LIMB REMOVAL ON THE PATH TAKEN OUT OF THE CENTRAL NERVOUS-SYSTEM, DEVELOPMENTAL BIOLOGY 93: 206 (1982).","journal-title":"DEVELOPMENTAL BIOLOGY"},{"key":"e_1_2_1_84_1","unstructured":"WILLIAMS A.F. COMMUNICATION."},{"key":"e_1_2_1_85_1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0167-5699(87)90016-8","volume":"8","year":"1987","unstructured":"WILLIAMS, A.F., A YEAR IN THE LIFE OF THE IMMUNOGLOBULIN SUPERFAMILY, IMMUNOLOGY TODAY 8: 298 (1987).","journal-title":"IMMUNOLOGY TODAY"},{"key":"e_1_2_1_86_1","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/0092-8674(88)90574-0","volume":"53","year":"1988","unstructured":"ZINN, K, SEQUENCE-ANALYSIS AND NEURONAL EXPRESSION OF FASCICLIN-I IN GRASSHOPPER AND DROSOPHILA, CELL 53: 577 (1988).","journal-title":"CELL"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.3187519","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T21:21:16Z","timestamp":1705180876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.3187519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,11,4]]},"references-count":86,"journal-issue":{"issue":"4879","published-print":{"date-parts":[[1988,11,4]]}},"alternative-id":["10.1126\/science.3187519"],"URL":"https:\/\/doi.org\/10.1126\/science.3187519","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,11,4]]}}}