{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:54:00Z","timestamp":1761580440044},"reference-count":26,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4344","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1978,5,26]]},"abstract":"<jats:p>Mortality and morbidity from infectious diseases in the United States have declined more than 90 percent since 1900. Factors believed to be responsible for this decline include changes in the natural history of disease, sanitation, quarantine measures, control of nonhuman vectors, antibacterial drugs, and immunization. The contributions of each of these factors differ among the various infectious diseases; except for smallpox and diphtheria control, immunization had little effect until after World War II. The success of present and future immunization programs is endangered by public and physician complacency and by complex legal and ethical problems related to informed consent and responsibility for rare, vaccine-related injury.<\/jats:p>","DOI":"10.1126\/science.347579","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T16:35:25Z","timestamp":1160066125000},"page":"902-907","source":"Crossref","is-referenced-by-count":15,"title":["Immunization Against Infectious Disease"],"prefix":"10.1126","volume":"200","author":[{"suffix":"Jr.","given":"Edward A.","family":"Mortimer","sequence":"first","affiliation":[{"name":"Elisabeth Severance Prentiss Professor of Community Health and Pediatrics and Chairman of the Department of Community Health at Case Western Reserve University School of Medicine, Cleveland, Ohio 44106."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","unstructured":"Institute of Medicine Evaluation of Poliomyelitis Vaccines (1977)."},{"key":"e_1_2_1_2_1","unstructured":"Bureau of the Census Historical Statistics of the United States Colonial Times to 1970 (1975)."},{"key":"e_1_2_1_3_1","first-page":"339","volume":"20","year":"1971","unstructured":"MORBIDITY MORTALITY 20: 339 (1971).","journal-title":"MORBIDITY MORTALITY"},{"key":"e_1_2_1_4_1","first-page":"178","volume":"21","year":"1972","unstructured":"MORBIDITY MORTALITY 21: 178 (1972).","journal-title":"MORBIDITY MORTALITY"},{"key":"e_1_2_1_5_1","first-page":"247","volume":"26","year":"1977","unstructured":"MORBIDITY MORTALITY 26: 247 (1977).","journal-title":"MORBIDITY MORTALITY"},{"key":"e_1_2_1_6_1","first-page":"329","volume":"26","year":"1977","unstructured":"MORBIDITY MORTALITY 26: 329 (1977).","journal-title":"MORBIDITY MORTALITY"},{"key":"e_1_2_1_7_1","first-page":"1","volume":"27","year":"1978","unstructured":"MORBIDITY MORTALITY 27: 1 (1978).","journal-title":"MORBIDITY MORTALITY"},{"key":"e_1_2_1_8_1","unstructured":"REPORT COMMITTEE INF (1977)."},{"key":"e_1_2_1_9_1","unstructured":"Reported Morbidity and Mortality Annual Summary 1976 (1977)."},{"key":"e_1_2_1_10_1","unstructured":"SPECIAL REPORTS MORT (1906)."},{"key":"e_1_2_1_11_1","unstructured":"Center for Disease Control United States Immunization Survey: 1975 (1976)."},{"key":"e_1_2_1_12_1","unstructured":"VITAL STATISTICS U A 2 (1977)."},{"key":"e_1_2_1_13_1","unstructured":"Whooping Cough Vaccination. 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