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However, the pharyngeal cells of all nine rheumatic heart disease patients tested had increased avidity for adherence for a rheumatic fever-associated strain of streptococcus compared to the pharyngeal cells obtained from age- and sex-matched controls. Increased streptococcal adherence to pharyngeal cells of rheumatic fever-prone patients may play a role in the pathogenesis of rheumatic fever.<\/jats:p>","DOI":"10.1126\/science.351810","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T16:35:25Z","timestamp":1160066125000},"page":"455-457","source":"Crossref","is-referenced-by-count":36,"title":["Adherence of Group A Streptococci to Pharyngeal Cells: A Role In The Pathogenesis of Rheumatic Fever"],"prefix":"10.1126","volume":"201","author":[{"given":"Daniel S.","family":"Selinger","sequence":"first","affiliation":[{"name":"Medical Service, Veterans Administration Hospital, and Bernalillo County Medical Center, University of New Mexico School of Medicine, Albuquerque 87108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Julie","sequence":"additional","affiliation":[{"name":"Medical Service, Veterans Administration Hospital, and Bernalillo County Medical Center, University of New Mexico School of Medicine, Albuquerque 87108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William P.","family":"Reed","sequence":"additional","affiliation":[{"name":"Medical Service, Veterans Administration Hospital, and Bernalillo County Medical Center, University of New Mexico School of Medicine, Albuquerque 87108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Ralph C.","family":"Williams","sequence":"additional","affiliation":[{"name":"Medical Service, Veterans Administration Hospital, and Bernalillo County Medical Center, University of New Mexico School of Medicine, Albuquerque 87108"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/iai.17.3.546-549.1977","volume":"17","year":"1977","unstructured":"ALY, R, BACTERIAL ADHERENCE TO NASAL MUCOSAL CELLS, INFECTION AND IMMUNITY 17: 546 (1977).","journal-title":"INFECTION AND IMMUNITY"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1084\/jem.143.4.759","volume":"143","year":"1976","unstructured":"BEACHEY, E.H., EPITHELIAL-CELL BINDING OF GROUP-A STREPTOCOCCI BY LIPOTEICHOIC ACID ON FIMBRIAE DENUDED OF M-PROTEIN, JOURNAL OF EXPERIMENTAL MEDICINE 143: 759 (1976).","journal-title":"JOURNAL OF EXPERIMENTAL MEDICINE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1093\/infdis\/136.2.278","volume":"136","year":"1977","unstructured":"BISNO, A.L., STREPTOCOCCAL INFECTIONS THAT FAIL TO CAUSE RECURRENCES OF RHEUMATIC-FEVER, JOURNAL OF INFECTIOUS DISEASES 136: 278 (1977).","journal-title":"JOURNAL OF INFECTIOUS DISEASES"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1056\/NEJM197009102831103","volume":"283","year":"1970","unstructured":"BISNO, A.L., CONTRASTING EPIDEMIOLOGY OF ACUTE RHEUMATIC FEVER AND ACUTE GLOMERULONEPHRITIS - NATURE OF ANTECEDENT STREPTOCOCCAL INFECTION, NEW ENGLAND JOURNAL OF MEDICINE 283: 561 (1970).","journal-title":"NEW ENGLAND JOURNAL OF MEDICINE"},{"key":"e_1_2_1_5_1","first-page":"99","year":"1977","unstructured":"Brewerton, D. 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