{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:47:23Z","timestamp":1791910043257,"version":"4.3.4"},"reference-count":16,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4686","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1985,2]]},"abstract":"<jats:p>\n            It has been generally accepted that infected fleas do not pass on\n            <jats:italic>Rickettsia mooseri<\/jats:italic>\n            , or indeed any other known pathogen, to their progeny. It is reported here that such transovarial transmission does occur in laboratory-infected\n            <jats:italic>Xenopsylla cheopis<\/jats:italic>\n            fleas. By means of the direct fluorescent antibody test,\n            <jats:italic>Rickettsia mooseri<\/jats:italic>\n            was observed in cells of the hemolymph of infected fleas. As many as 11 percent of the adults and 2.9 percent of the larvae of the generation reared therefrom, had demonstrable rickettsiae. Moreover, batches of the F\n            <jats:sub>1<\/jats:sub>\n            fleas were capable of transmitting the infection to more than 18 percent of the rats they infested. The data support the contention that\n            <jats:italic>Xenopsylla cheopis<\/jats:italic>\n            fleas play an important role in the maintenance of murine typhus in rats in nature.\n          <\/jats:p>","DOI":"10.1126\/science.3966162","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T19:42:50Z","timestamp":1160077370000},"page":"543-545","source":"Crossref","is-referenced-by-count":50,"title":["Transovarial Transmission of Murine Typhus Rickettsiae in\n            <i>Xenopsylla cheopis<\/i>\n            Fleas"],"prefix":"10.1126","volume":"227","author":[{"given":"A.","family":"Farhang-Azad","sequence":"first","affiliation":[{"name":"Department of Microbiology, University of Maryland School of Medicine, Baltimore 21201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Traub","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Maryland School of Medicine, Baltimore 21201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Baqar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Maryland School of Medicine, Baltimore 21201"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.4269\/ajtmh.1984.33.1017","volume":"33","year":"1984","unstructured":"ARANGOJARAMILLO, S, EXPERIMENTAL-INFECTION WITH RICKETTSIA-MOOSERI AND ANTIBODY-RESPONSE OF ADULT AND NEWBORN LABORATORY RATS, AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 33: 1017 (1984).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_2_1","first-page":"23","volume":"32","year":"1977","unstructured":"BIBIKOVA, V.A., ANN REV ENTOMOL 32: 23 (1977).","journal-title":"ANN REV ENTOMOL"},{"key":"e_1_2_1_3_1","first-page":"279","year":"1980","unstructured":"BURGDORFER, W, CRC HDB SERIES ZOON: 279 (1980).","journal-title":"CRC HDB SERIES ZOON"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.2307\/4580289","volume":"46","year":"1931","unstructured":"CEDER, E.T., PUBLIC HEALTH REPORTS 46: 3103 (1931).","journal-title":"PUBLIC HEALTH REPORTS"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.4269\/ajtmh.1983.32.1392","volume":"32","year":"1983","unstructured":"FARHANGAZAD, A, RICKETTSIA MOOSERI INFECTION IN THE FLEAS LEPTOPSYLLA-SEGNIS AND XENOPSYLLA-CHEOPIS, AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 32: 1392 (1983).","journal-title":"AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_6_1","first-page":"363","year":"1981","unstructured":"FARHANGAZAD, A, RICKETTSIAE RICKETTS: 363 (1981).","journal-title":"RICKETTSIAE RICKETTS"},{"key":"e_1_2_1_7_1","unstructured":"HARWOOD R.F. 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