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The amebic lysates were shown to contain serotonin by radioimmunoassay, high-performance liquid chromatography, and thin-layer chromatography. These results suggest that the serotonin present in\n            <jats:italic>Entamoeba histolytica<\/jats:italic>\n            may be important in the diarrhea seen in amebiasis.\n          <\/jats:p>","DOI":"10.1126\/science.6308760","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T18:37:18Z","timestamp":1160073438000},"page":"762-764","source":"Crossref","is-referenced-by-count":58,"title":["<i>Entamoeba histolytica<\/i>\n            Causes Intestinal Secretion: Role of Serotonin"],"prefix":"10.1126","volume":"221","author":[{"given":"Katherine","family":"McGowan","sequence":"first","affiliation":[{"name":"Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Kane","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Asarkof","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Wicks","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Guerina","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kellum","sequence":"additional","affiliation":[{"name":"Department of Surgery, New England Medical Center Hospital, Boston, Massachusetts 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherri","family":"Baron","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Downstate Medical School, Brooklyn, New York 11203"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan R.","family":"Gintzler","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Downstate Medical School, Brooklyn, New York 11203"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Donowitz","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Physiology, Tufts University Schools of Medicine, Dental Medicine, and Veterinary Medicine, and Sackler School of Graduate Biomedical Sciences, Boston 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"120","volume":"73","year":"1979","unstructured":"BOS, H.J., TOXINS OF ENTAMOEBA-HISTOLYTICA, TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE 73: 120 (1979).","journal-title":"TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1172\/JCI109919","volume":"66","year":"1980","unstructured":"DHARMSATHAPHORN, K, EFFECT OF SOMATOSTATIN ON ION-TRANSPORT IN THE RAT COLON, JOURNAL OF CLINICAL INVESTIGATION 66: 813 (1980).","journal-title":"JOURNAL OF CLINICAL INVESTIGATION"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0035-9203(78)90144-X","volume":"72","year":"1978","unstructured":"DIAMOND, L.S., NEW MEDIUM FOR AXENIC CULTIVATION OF ENTAMOEBA-HISTOLYTICA AND OTHER ENTAMOEBA, TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE 72: 431 (1978).","journal-title":"TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE"},{"key":"e_1_2_1_4_1","first-page":"G463","volume":"239","year":"1980","unstructured":"DONOWITZ, M, EFFECT OF SEROTONIN ON ACTIVE ELECTROLYTE TRANSPORT IN RABBIT ILEUM, GALLBLADDER, AND COLON, AMERICAN JOURNAL OF PHYSIOLOGY 239: G463 (1980).","journal-title":"AMERICAN JOURNAL OF PHYSIOLOGY"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1172\/JCI109862","volume":"66","year":"1980","unstructured":"DONOWITZ, M, CALCIUM DEPENDENCE OF SEROTONIN-INDUCED CHANGES IN RABBIT ILEAL ELECTROLYTE TRANSPORT, JOURNAL OF CLINICAL INVESTIGATION 66: 341 (1980).","journal-title":"JOURNAL OF CLINICAL INVESTIGATION"},{"key":"e_1_2_1_6_1","unstructured":"DONOWITZ M unpublished data."},{"key":"e_1_2_1_7_1","first-page":"2800","volume":"75","year":"1978","unstructured":"FIELD, M, HEAT-STABLE ENTEROTOXIN OF ESCHERICHIA-COLI - 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