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The greatest identity occurs with residues considered most important in neurotoxicity, including those interacting with the acetylcholine binding site of the acetylcholine receptor. Because of the similarity between the glycoprotein and the receptor-binding region of the neurotoxins, this region of the viral glycoprotein may function as a recognition site for the acetylcholine receptor. Direct binding of the rabies virus glycoprotein to the acetylcholine receptor could contribute to the neurotropism of this virus.<\/jats:p>","DOI":"10.1126\/science.6494916","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T19:41:59Z","timestamp":1160077319000},"page":"847-848","source":"Crossref","is-referenced-by-count":138,"title":["Amino Acid Sequence Similarity Between Rabies Virus Glycoprotein and Snake Venom Curaremimetic Neurotoxins"],"prefix":"10.1126","volume":"226","author":[{"given":"Thomas L.","family":"Lentz","sequence":"first","affiliation":[{"name":"Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul T.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Hawrot","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Speicher","sequence":"additional","affiliation":[{"name":"Protein Chemistry Laboratory, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/294275a0","volume":"294","year":"1981","unstructured":"ANILIONIS, A, STRUCTURE OF THE GLYCOPROTEIN GENE IN RABIES VIRUS, NATURE 294: 275 (1981).","journal-title":"NATURE"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1088\/0022-3719\/5\/4\/002","volume":"5","year":"1972","unstructured":"BARKER, M.I., VELOCITY AUTOCORRELATION FUNCTION AND DIFFUSION-COEFFICIENT IN A LIQUID .2., JOURNAL OF PHYSICS PART C SOLID STATE PHYSICS 5: 353 (1972).","journal-title":"JOURNAL OF PHYSICS PART C SOLID STATE PHYSICS"},{"key":"e_1_2_1_3_1","unstructured":"Barker W.C. 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