{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T22:52:39Z","timestamp":1771627959083,"version":"3.50.1"},"reference-count":11,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4658","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1984,7,13]]},"abstract":"<jats:p>The idea that sustained microgravity will result in altered otolith input requiring a modification of postural control was explored by using the pathway that links the otolith organs and spinal motoneurons. Two related methods were used. First, the Hoffmann reflex was used to measure at specific times the excitability of the soleus-spinal motoneuron pool during a brief unexpected linear acceleration. Second, extensive dynamic postural testing with a moving platform was done before and after flight. The Hoffmann reflex amplitude, reflecting otolith-modulated motoneuron sensitivity, was low in flight after adaptation, and its postflight potentiation may have been dependent on rate of adaptation. The strength of inflight motion sickness symptoms was related to postflight Hoffmann reflex amplitude. Dynamic posture tests showed significant deviations from the results obtained before flight. The strategy used for balance on the moving platform was modified, and the behavior of the subjects suggested a decrease in awareness of the direction and magnitude of the motion.<\/jats:p>","DOI":"10.1126\/science.6729475","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T19:41:59Z","timestamp":1160077319000},"page":"212-214","source":"Crossref","is-referenced-by-count":53,"title":["Vestibulospinal Reflexes as a Function of Microgravity"],"prefix":"10.1126","volume":"225","author":[{"given":"Millard F.","family":"Reschke","sequence":"first","affiliation":[{"name":"Space Biomedical Research Institute, NASA-Johnson Space Center, Houston, Texas 77058"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Kresge Hearing Research Institute, University of Michigan, Ann Arbor 48104"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry L.","family":"Homick","sequence":"additional","affiliation":[{"name":"Space Biomedical Research Institute, NASA-Johnson Space Center, Houston, Texas 77058"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"35","year":"1977","unstructured":"Anderson, D. J., Proceedings of the 1977 San Diego Bioengineering Symposium: 35 (1977).","journal-title":"Proceedings of the 1977 San Diego Bioengineering Symposium"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0196-0709(80)80089-5","volume":"1","year":"1980","unstructured":"ANDRES, R.O., AMERICAN JOURNAL OF OTOLARYNGOLOGY 1: 197 (1980).","journal-title":"AMERICAN JOURNAL OF OTOLARYNGOLOGY"},{"key":"e_1_2_1_3_1","first-page":"56","volume":"292","year":"1983","unstructured":"CLEMENT, G, CR ACAD SCI 292: 56 (1983).","journal-title":"CR ACAD SCI"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1136\/jnnp.40.5.448","volume":"40","year":"1977","unstructured":"GREENWOOD, R, MONOSYNAPTIC REFLEXES IN FALLING MAN, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 40: 448 (1977).","journal-title":"JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3109\/00016487709128871","volume":"83","year":"1977","unstructured":"HOMICK, J.L., POSTURAL EQUILIBRIUM FOLLOWING EXPOSURE TO WEIGHTLESS SPACE-FLIGHT, ACTA OTO-LARYNGOLOGICA 83: 455 (1977).","journal-title":"ACTA OTO-LARYNGOLOGICA"},{"key":"e_1_2_1_6_1","first-page":"277","year":"1973","unstructured":"Hugon, M., Development in Electromyography and Clinical Neurophysiology: 277 (1973).","journal-title":"Development in Electromyography and Clinical Neurophysiology"},{"key":"e_1_2_1_7_1","first-page":"195","volume":"153","year":"1960","unstructured":"MATTHEWS, B, TENDON REFLEXES IN FREE FALL, PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 153: 195 (1960).","journal-title":"PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES"},{"key":"e_1_2_1_8_1","unstructured":"Reschke M. F. Experimental Brain Research in press."},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1152\/jn.1981.45.4.644","volume":"45","year":"1981","unstructured":"WATT, DGD, EFFECT OF VERTICAL LINEAR ACCELERATION ON H-REFLEX IN DECEREBRATE CAT .1. TRANSIENT STIMULI, JOURNAL OF NEUROPHYSIOLOGY 45: 644 (1981).","journal-title":"JOURNAL OF NEUROPHYSIOLOGY"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0010-468X(84)90025-4","volume":"18","year":"1984","unstructured":"Werness, S. A. S., Computer Methods and Programs in Biomedicine 18: 77 (1984).","journal-title":"Computer Methods and Programs in Biomedicine"},{"key":"e_1_2_1_11_1","unstructured":"Yakovleava I. Y. paper presented at the International Astronautical Federation 28th Congress Prague (1977)."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.6729475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T22:22:47Z","timestamp":1705270967000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.6729475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,7,13]]},"references-count":11,"journal-issue":{"issue":"4658","published-print":{"date-parts":[[1984,7,13]]}},"alternative-id":["10.1126\/science.6729475"],"URL":"https:\/\/doi.org\/10.1126\/science.6729475","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,7,13]]}}}