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Ac-rfwink-NH\n            <jats:sub>2<\/jats:sub>\n            was shown to be a potent agonist at the \u03bc receptor and induced long-lasting analgesia in mice. Analgesia produced by intraperitoneally administered Ac-rfwink-NH\n            <jats:sub>2<\/jats:sub>\n            was blocked by intracerebroventricular administration of naloxone, demonstrating that this peptide may cross the blood-brain barrier.\n          <\/jats:p>","DOI":"10.1126\/science.7801131","type":"journal-article","created":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T00:01:25Z","timestamp":1160092885000},"page":"2019-2022","source":"Crossref","is-referenced-by-count":154,"title":["An All D-Amino Acid Opioid Peptide with Central Analgesic Activity from a Combinatorial Library"],"prefix":"10.1126","volume":"266","author":[{"given":"C. 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