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Measurements from Gage's skull and modern neuroimaging techniques were used to reconstitute the accident and determine the probable location of the lesion. The damage involved both left and right prefrontal cortices in a pattern that, as confirmed by Gage's modern counterparts, causes a defect in rational decision making and the processing of emotion.<\/jats:p>","DOI":"10.1126\/science.8178168","type":"journal-article","created":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T00:01:25Z","timestamp":1160092885000},"page":"1102-1105","source":"Crossref","is-referenced-by-count":1028,"title":["The Return of Phineas Gage: Clues About the Brain from the Skull of a Famous Patient"],"prefix":"10.1126","volume":"264","author":[{"given":"Hanna","family":"Damasio","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Iowa Hospitals &amp; Clinics, Iowa City, IA 52242, USA."},{"name":"Salk Institute for Biological Research, San Diego, CA 92186-5800, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Grabowski","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Iowa Hospitals &amp; Clinics, Iowa City, IA 52242, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Iowa Hospitals &amp; Clinics, Iowa City, IA 52242, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert M.","family":"Galaburda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Harvard Medical School, Beth Israel Hospital, Boston, MA 02215, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio R.","family":"Damasio","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Iowa Hospitals &amp; Clinics, Iowa City, IA 52242, USA."},{"name":"Salk Institute for Biological Research, San Diego, CA 92186-5800, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/cne.902860306","volume":"286","year":"1989","unstructured":"Barbas, H, Journal of Comparative Neurology 286: 353 (1989).","journal-title":"Journal of Comparative Neurology"},{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-0277(94)90018-3"},{"key":"e_1_2_1_3_1","first-page":"337","volume":"6","year":"1865","unstructured":"BROCA, P, BULLETIN DE LA SOCIETE ANTHROPOLOGIQUE 6: 337 (1865).","journal-title":"BULLETIN DE LA SOCIETE ANTHROPOLOGIQUE"},{"key":"e_1_2_1_4_1","first-page":"217","year":"1991","unstructured":"Damasio, A. 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