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We suggest that\n            <jats:italic>Fasciola hepatica<\/jats:italic>\n            , which synthesizes and releases large amounts of proline, induces enlargement of the bile duct by a similar mechanism.\n          <\/jats:p>","DOI":"10.1126\/science.929191","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T16:03:07Z","timestamp":1160064187000},"page":"1157-1159","source":"Crossref","is-referenced-by-count":50,"title":["Fascioliasis: Role of Proline in Bile Duct Hyperplasia"],"prefix":"10.1126","volume":"198","author":[{"given":"Hadar","family":"Isseroff","sequence":"first","affiliation":[{"name":"Department of Biology, State University College at Buffalo, Buffalo, New York 14222"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph T.","family":"Sawma","sequence":"additional","affiliation":[{"name":"Department of Biology, State University College at Buffalo, Buffalo, New York 14222"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Reino","sequence":"additional","affiliation":[{"name":"Department of Biology, State University College at Buffalo, Buffalo, New York 14222"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/BF02023850","volume":"3","year":"1973","unstructured":"CHVAPIL, M, POOL OF FREE PROLINE IN ACUTE AND CHRONIC LIVER INJURY AND ITS EFFECT ON SYNTHESIS OF COLLAGEN AND GLOBULAR PROTEINS, AGENTS AND ACTIONS 3: 38 (1973).","journal-title":"AGENTS AND ACTIONS"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/1981011a0","volume":"198","year":"1963","unstructured":"DAWES, B, FASCIOLA HEPATICA L., A TISSUE FEEDER, NATURE 198: 1011 (1963).","journal-title":"NATURE"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1017\/S0031182000072590","volume":"53","year":"1963","unstructured":"DAWES, B, HYPERPLASIA OF BILE DUCT IN FASCIOLIASIS AND ITS RELATION TO PROBLEM OF NUTRITION IN LIVER-FLUKE, FASCIOLA HEPATICA L., PARASITOLOGY 53: 123 (1963).","journal-title":"PARASITOLOGY"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.2307\/3278709","volume":"60","year":"1974","unstructured":"ERTEL, J, PROLINE IN FASCIOLIASIS .1. 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