{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T05:25:57Z","timestamp":1751865957291},"reference-count":26,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"4249","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1976,7,16]]},"abstract":"<jats:p>Intracerebral injection of L-proline, 1 minute after one-trial avoidance training of chicks, impaired memory 24 hours later. Chicks injected with proline 1 or 4 hours after training and controls injected with L-isoleucine at intervals after training, showed no impairment of memory 24 hours after training. The retrograde impairment of long-term memory induced by proline occurred without the convulsions or electrographic events usually associated with retrograde amnesic treatments.<\/jats:p>","DOI":"10.1126\/science.945612","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T15:51:28Z","timestamp":1160063488000},"page":"242-244","source":"Crossref","is-referenced-by-count":48,"title":["Memory: Proline Induces Retrograde Amnesia in Chicks"],"prefix":"10.1126","volume":"193","author":[{"given":"Arthur","family":"Cherkin","sequence":"first","affiliation":[{"name":"Psychobiology Research Laboratory, Veterans Administration Hospital, Sepulveda, California 01343"},{"name":"Departments of Anesthesiology and Psychiatry, University of California School of Medicine, Los Angeles 90024"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Eckardt","sequence":"additional","affiliation":[{"name":"Psychobiology Research Laboratory, Veterans Administration Hospital, Sepulveda, California 01343"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren K.","family":"Gerbrandt","sequence":"additional","affiliation":[{"name":"Department of Psychology, California State University, Northridge 91324"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.158.3808.1600"},{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1973.sp010273"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/0031-9384(72)90006-6","volume":"9","year":"1972","unstructured":"BRESNAHAN, E, PHYSIOLOGY & BEHAVIOR 9: 513 (1972).","journal-title":"PHYSIOLOGY & BEHAVIOR"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0045749"},{"key":"e_1_2_1_5_1","first-page":"459","volume":"17","year":"1974","unstructured":"CHERKIN, A, ERGEBNISSE DER EXPERIMENTELLEN MEDIZIN 17: 459 (1974).","journal-title":"ERGEBNISSE DER EXPERIMENTELLEN MEDIZIN"},{"key":"e_1_2_1_6_1","first-page":"1094","volume":"63","year":"1969","unstructured":"CHERKIN, A, KINETICS OF MEMORY CONSOLIDATION - ROLE OF AMNESIC TREATMENT PARAMETERS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 63: 1094 (1969).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0028-3932(68)90009-2","volume":"6","year":"1968","unstructured":"DORFMAN, L.J., NEUROPSYCHOLOGIA 6: 373 (1968).","journal-title":"NEUROPSYCHOLOGIA"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.141.3575.57"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/0031-9384(73)90221-7","volume":"10","year":"1973","unstructured":"FLOOD, J.F., INFLUENCE OF DURATION OF PROTEIN-SYNTHESIS INHIBITION ON MEMORY, PHYSIOLOGY & BEHAVIOR 10: 555 (1973).","journal-title":"PHYSIOLOGY & BEHAVIOR"},{"key":"e_1_2_1_10_1","unstructured":"Gerbrandt L. K. in preparation."},{"key":"e_1_2_1_11_1","first-page":"268","volume":"3","year":"1973","unstructured":"GERBRANDT, L.K., SOCIETY FOR NEUROSCIENCE. ABSTRACTS 3: 268 (1973).","journal-title":"SOCIETY FOR NEUROSCIENCE. ABSTRACTS"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0091-6773(75)92131-8","volume":"15","year":"1975","unstructured":"GOLD, P.E., AMNESIA PRODUCED BY UNILATERAL, SUBSEIZURE, ELECTRICAL-STIMULATION OF AMYGDALA IN RATS, BEHAVIORAL BIOLOGY 15: 95 (1975).","journal-title":"BEHAVIORAL BIOLOGY"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/0014-4886(69)90117-4","volume":"23","year":"1969","unstructured":"LEETENG, E, ELECTROCORTICOGRAMS FOWLLOWING THRESHOLD TRANSCRANIAL ELECTROSHOCK FOR RETROGRADE AMNESIA IN CHICKS, EXPERIMENTAL NEUROLOGY 23: 485 (1969).","journal-title":"EXPERIMENTAL NEUROLOGY"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1037\/h0026791","volume":"67","year":"1969","unstructured":"LEETENG, E, RETROGRADE AMNESIA IN RELATION TO SUBCONVULSIVE AND CONVULSIVE CURRENTS IN CHICKS, JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 67: 135 (1969).","journal-title":"JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY"},{"key":"e_1_2_1_15_1","first-page":"926","volume":"56","year":"1966","unstructured":"LEETENG, E, MEMORY CONSOLIDATION OF 1-TRIAL LEARNING IN CHICKS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 56: 926 (1966).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1037\/h0031575","volume":"77","year":"1971","unstructured":"MCDONOUGH, J.H., AMNESIA PRODUCED BY BRIEF ELECTRICAL STIMULATION OF AMYGDALA OR DORSAL HIPPOCAMPUS IN CATS, JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 77: 171 (1971).","journal-title":"JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY"},{"key":"e_1_2_1_17_1","first-page":"3","year":"1972","unstructured":"McGaugh, J. L., Memory Consolidation: 3 (1972).","journal-title":"Memory Consolidation"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.153.3742.1351"},{"key":"e_1_2_1_19_1","first-page":"340","volume":"20","year":"1961","unstructured":"PEARLMAN, C. A., FEDERATION PROCEEDINGS 20: 340 (1961).","journal-title":"FEDERATION PROCEEDINGS"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0044245"},{"key":"e_1_2_1_21_1","first-page":"175","year":"1970","unstructured":"Rail, W., Excitatory Synaptic Mechanisms, Proceedings of the 5th International Meeting of Neurobiologists: 175 (1970).","journal-title":"Excitatory Synaptic Mechanisms, Proceedings of the 5th International Meeting of Neurobiologists"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0006-8993(74)90148-6","volume":"66","year":"1974","unstructured":"SQUIRE, L.R., ANISOMYCIN, LIKE OTHER INHIBITORS OF CEREBRAL PROTEIN-SYNTHESIS, IMPAIRS LONG-TERM-MEMORY OF A DISCRIMINATION TASK, BRAIN RESEARCH 66: 301 (1974).","journal-title":"BRAIN RESEARCH"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0006-8993(74)90843-9","volume":"81","year":"1974","unstructured":"VANHARREVELD, A, INVOLVEMENT OF GLUTAMATE IN MEMORY FORMATION, BRAIN RESEARCH 81: 455 (1974).","journal-title":"BRAIN RESEARCH"},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/0014-4886(75)90055-2","volume":"49","year":"1975","unstructured":"VANHARREVELD, A, SWELLING OF DENDRITIC SPINES IN FASCIA DENTATA AFTER STIMULATION OF PERFORANT FIBERS AS A MECHANISM OF POST-TETANIC POTENTIATION, EXPERIMENTAL NEUROLOGY 49: 736 (1975).","journal-title":"EXPERIMENTAL NEUROLOGY"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1111\/j.1471-4159.1973.tb00065.x","volume":"20","year":"1973","unstructured":"VANHARREVELD, A, EFFECTS OF AMINO-ACIDS ON ISOLATED CHICKEN RETINA, AND ON ITS RESPONSE TO GLUTAMATE STIMULATION, JOURNAL OF NEUROCHEMISTRY 20: 947 (1973).","journal-title":"JOURNAL OF NEUROCHEMISTRY"},{"key":"e_1_2_1_26_1","first-page":"379","volume":"1","year":"1970","unstructured":"ZORNETZER, S, J NEUROBIOL 1: 379 (1970).","journal-title":"J NEUROBIOL"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.945612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T17:52:54Z","timestamp":1705341174000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.945612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,7,16]]},"references-count":26,"journal-issue":{"issue":"4249","published-print":{"date-parts":[[1976,7,16]]}},"alternative-id":["10.1126\/science.945612"],"URL":"https:\/\/doi.org\/10.1126\/science.945612","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,7,16]]}}}