{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T01:51:26Z","timestamp":1792288286795,"version":"4.4.0"},"reference-count":35,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6241","license":[{"start":{"date-parts":[[2016,6,19]],"date-time":"2016-06-19T00:00:00Z","timestamp":1466294400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R00 MH092715"],"award-info":[{"award-number":["R00 MH092715"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute for Mental Health","doi-asserted-by":"publisher","award":["5R37MH087027"],"award-info":[{"award-number":["5R37MH087027"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["EXC 307"],"award-info":[{"award-number":["EXC 307"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"MIT Picower Innovation Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2015,6,19]]},"abstract":"<jats:title>Signal flow during sensorimotor choices<\/jats:title>\n                  <jats:p>\n                    Little is known about the flow of task signals across the brain. Siegel\n                    <jats:italic>et al.<\/jats:italic>\n                    simultaneously recorded from multiple units in the sensory, parietal, prefrontal, and motor cortex while monkeys were cued to perform one among two possible simple tasks. The proportion of neurons coding for stimuli, cues, tasks, and choices, and their response latency, varied across regions. Parietal and prefrontal brain regions encoded task information and choices with the same latency. Interestingly, all brain areas encoded all types of information. However, they differed functionally according to the proportions of neurons and their response latency.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6241\" page=\"1352\" related-article-type=\"in-this-issue\" vol=\"348\" xlink:href=\"10.1126\/science.aab0551\">1352<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aab0551","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T14:10:13Z","timestamp":1434636613000},"page":"1352-1355","source":"Crossref","is-referenced-by-count":476,"title":["Cortical information flow during flexible sensorimotor decisions"],"prefix":"10.1126","volume":"348","author":[{"given":"Markus","family":"Siegel","sequence":"first","affiliation":[{"name":"Centre for Integrative Neuroscience and MEG Center, University of T\u00fcbingen, T\u00fcbingen, Germany."},{"name":"Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Buschman","sequence":"additional","affiliation":[{"name":"Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."},{"name":"Princeton Neuroscience Institute and Department of Psychology, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Earl K.","family":"Miller","sequence":"additional","affiliation":[{"name":"Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3509"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3585-11.2012"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.2.628"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05078"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3918"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.01.039"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/5739"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1121084109"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.291.5502.312"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.07.066"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1017\/S095252380000715X"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07821"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2772635"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/35082081"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.12.023"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2006.18.6.974"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.18.030195.001205"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.23.1.315"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.26.041002.131039"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12742"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1037\/0096-3445.113.4.501"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2013.09.006"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.24.1.167"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3137"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.09.034"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14066"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms7177"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008973215925"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/35084005"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402773111"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00527.2012"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2008.07.014"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.66.3.1095"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1985.53.3.603"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989X.8.4.434"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.aab0551","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T12:06:52Z","timestamp":1705320412000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.aab0551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,19]]},"references-count":35,"journal-issue":{"issue":"6241","published-print":{"date-parts":[[2015,6,19]]}},"alternative-id":["10.1126\/science.aab0551"],"URL":"https:\/\/doi.org\/10.1126\/science.aab0551","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,19]]}}}