{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:39:40Z","timestamp":1790800780185,"version":"4.1.0"},"reference-count":34,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6268","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["91213066"],"award-info":[{"award-number":["91213066"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)"},{"name":"Ministry of Science and Culture of Lower Saxony"},{"name":"Innovative Medicines Initiative (IMI)","award":["115760"],"award-info":[{"award-number":["115760"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Coronaviruses in the Middle East<\/jats:title>\n                  <jats:p>\n                    Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory illness and kills about a third of people infected. The virus is common in dromedary camels, which can be a source of human infections. In a survey for MERSCoV in over 1300 Saudi Arabian camels, Sabir\n                    <jats:italic>et al.<\/jats:italic>\n                    found that dromedaries share three coronavirus species with humans. Diverse MERS lineages in camels have caused human infections, which suggests that transfer among host species occurs quite easily. Haagmans\n                    <jats:italic>et al.<\/jats:italic>\n                    made a MERS-CoV vaccine for use in camels, using poxvirus as a vehicle. The vaccine significantly reduced virus excretion, which should help reduce the potential for transmission to humans, and conferred cross-immunity to camelpox infections.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6268\" page=\"81\" related-article-type=\"in-this-issue\" vol=\"351\" xlink:href=\"10.1126\/science.aac8608\">81<\/jats:related-article>\n                    , p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6268\" page=\"77\" related-article-type=\"in-this-issue\" vol=\"351\" xlink:href=\"10.1126\/science.aad1283\">77<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aad1283","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T00:14:02Z","timestamp":1450397642000},"page":"77-81","source":"Crossref","is-referenced-by-count":245,"title":["An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels"],"prefix":"10.1126","volume":"351","author":[{"given":"Bart L.","family":"Haagmans","sequence":"first","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith M. A.","family":"van den Brand","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Stalin","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asisa","family":"Volz","sequence":"additional","affiliation":[{"name":"German Centre for Infection Research (DZIF), Institute for Infectious Diseases and Zoonoses, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Wohlsein","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Veterinary Medicine, Hannover, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia L.","family":"Smits","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debby","family":"Schipper","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo M.","family":"Bestebroer","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisreen","family":"Okba","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Fux","sequence":"additional","affiliation":[{"name":"German Centre for Infection Research (DZIF), Institute for Infectious Diseases and Zoonoses, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Bensaid","sequence":"additional","affiliation":[{"name":"Institut de Recerca i Tecnologia Agroaliment\u00e0ries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA\u2013Universitat  Aut\u00f2noma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Solanes Foz","sequence":"additional","affiliation":[{"name":"Institut de Recerca i Tecnologia Agroaliment\u00e0ries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA\u2013Universitat  Aut\u00f2noma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thijs","family":"Kuiken","sequence":"additional","affiliation":[{"name":"Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Baumg\u00e4rtner","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Veterinary Medicine, Hannover, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim","family":"Segal\u00e9s","sequence":"additional","affiliation":[{"name":"UAB, CReSA, (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain."},{"name":"Departament de Sanitat i Anatomia Animals, Facultat de Veterin\u00e0ria, UAB, 08193 Bellaterra, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Sutter","sequence":"additional","affiliation":[{"name":"German Centre for Infection Research (DZIF), Institute for Infectious Diseases and Zoonoses, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert D. 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