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In proof-of-concept studies, Long\n                    <jats:italic>et al.<\/jats:italic>\n                    , Nelson\n                    <jats:italic>et al.<\/jats:italic>\n                    , and Tabebordbar\n                    <jats:italic>et al.<\/jats:italic>\n                    used adeno-associated virus-9 to deliver the CRISPR\/Cas9 gene-editing system to young mice with a mutation in the gene coding for dystrophin, a muscle protein deficient in patients with Duchenne muscular dystrophy. Gene editing partially restored dystrophin protein expression in skeletal and cardiac muscle and improved skeletal muscle function.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6271\" page=\"400\" related-article-type=\"in-this-issue\" vol=\"351\" xlink:href=\"10.1126\/science.aad5725\">400<\/jats:related-article>\n                    , p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6271\" page=\"403\" related-article-type=\"in-this-issue\" vol=\"351\" xlink:href=\"10.1126\/science.aad5143\">403<\/jats:related-article>\n                    , p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6271\" page=\"407\" related-article-type=\"in-this-issue\" vol=\"351\" xlink:href=\"10.1126\/science.aad5177\">407<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aad5725","type":"journal-article","created":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T22:33:48Z","timestamp":1451601228000},"page":"400-403","source":"Crossref","is-referenced-by-count":886,"title":["Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy"],"prefix":"10.1126","volume":"351","author":[{"given":"Chengzu","family":"Long","sequence":"first","affiliation":[{"name":"Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA."},{"name":"Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA."},{"name":"Sen. 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