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Ethionamide is potentiated by small molecules. Blondiaux\n                    <jats:italic>et al.<\/jats:italic>\n                    screened for more potent analogs and identified a lead compound called SMARt-420. This small molecule inactivates a TetR-like repressor, EthR2, and boosts ethionamide activation. SMARt-420 successfully promoted clearance of multidrug-resistant strains of\n                    <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                    from the lungs of mice.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6330\" page=\"1206\" related-article-type=\"in-this-issue\" vol=\"355\" xlink:href=\"10.1126\/science.aag1006\">1206<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aag1006","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T14:05:22Z","timestamp":1489673122000},"page":"1206-1211","source":"Crossref","is-referenced-by-count":150,"title":["Reversion of antibiotic resistance in\n                    <i>Mycobacterium tuberculosis<\/i>\n                    by spiroisoxazoline SMARt-420"],"prefix":"10.1126","volume":"355","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9762-7322","authenticated-orcid":false,"given":"Nicolas","family":"Blondiaux","sequence":"first","affiliation":[{"name":"Univ. 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