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Minutti\n                    <jats:italic>et al.<\/jats:italic>\n                    studied mouse models of helminth infection and fibrosis. They expressed surfactant protein A (a member of the complement component C1q family) in the lung, which enhanced interleukin-4 (IL-4)-mediated proliferation and activation of alveolar macrophages. This activation accelerated helminth clearance and reduced lung injury. In the peritoneum, C1q boosted macrophage activation for liver repair after bacterial infection. By a different approach, Bosurgi\n                    <jats:italic>et al.<\/jats:italic>\n                    discovered that after wounding caused by migrating helminths in the lung or during inflammation in the gut of mice, IL-4 and IL-13 act only in the presence of apoptotic cells to promote tissue repair by local macrophages.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6342\" page=\"1076\" related-article-type=\"in-this-issue\" vol=\"356\" xlink:href=\"10.1126\/science.aaj2067\">1076<\/jats:related-article>\n                    , p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6342\" page=\"1072\" related-article-type=\"in-this-issue\" vol=\"356\" xlink:href=\"10.1126\/science.aai8132\">1072<\/jats:related-article>\n                    ; see also p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6342\" page=\"1014\" related-article-type=\"in-this-issue\" vol=\"356\" xlink:href=\"10.1126\/science.aan6782\">1014<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aaj2067","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T21:00:39Z","timestamp":1494536439000},"page":"1076-1080","source":"Crossref","is-referenced-by-count":198,"title":["Local amplifiers of IL-4R\u03b1\u2013mediated macrophage activation promote repair in lung and liver"],"prefix":"10.1126","volume":"356","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9663-1928","authenticated-orcid":true,"given":"Carlos M.","family":"Minutti","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology I, 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