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Progress toward a vaccine has been impeded by the absence of mouse models suitable for studying the immune response to HCV. Billerbeck\n                    <jats:italic>et al.<\/jats:italic>\n                    found that a HCV-related virus isolated from New York City rats produces an infection in laboratory mice that shares several immunological features with human infections (see the Perspective by Klenerman and Barnes). Their initial analyses of the infected mice revealed that acute clearance of the virus was dependent on T cells but not on natural killer cells.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6347\" page=\"204\" related-article-type=\"in-this-issue\" vol=\"357\" xlink:href=\"10.1126\/science.aal1962\">204<\/jats:related-article>\n                    ; see also p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6347\" page=\"129\" related-article-type=\"in-this-issue\" vol=\"357\" xlink:href=\"10.1126\/science.aao0184\">129<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aal1962","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T16:55:14Z","timestamp":1500483314000},"page":"204-208","source":"Crossref","is-referenced-by-count":142,"title":["Mouse models of acute and chronic hepacivirus infection"],"prefix":"10.1126","volume":"357","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0477-1748","authenticated-orcid":false,"given":"Eva","family":"Billerbeck","sequence":"first","affiliation":[{"name":"Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6191-2084","authenticated-orcid":false,"given":"Raphael","family":"Wolfisberg","sequence":"additional","affiliation":[{"name":"Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2527-5751","authenticated-orcid":false,"given":"Ulrik","family":"Fahn\u00f8e","sequence":"additional","affiliation":[{"name":"Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4572-3862","authenticated-orcid":false,"given":"Jing W.","family":"Xiao","sequence":"additional","affiliation":[{"name":"Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrine","family":"Quirk","sequence":"additional","affiliation":[{"name":"Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2415-9203","authenticated-orcid":false,"given":"Joseph M.","family":"Luna","sequence":"additional","affiliation":[{"name":"Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5333-9284","authenticated-orcid":false,"given":"John M.","family":"Cullen","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8414-2959","authenticated-orcid":false,"given":"Alex S.","family":"Hartlage","sequence":"additional","affiliation":[{"name":"Center for Vaccines and Immunity, The Research Institute at Nationwide Children\u2019s Hospital and Department of Pediatrics, Ohio State University, Columbus, OH, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-6873","authenticated-orcid":false,"given":"Luis","family":"Chiriboga","sequence":"additional","affiliation":[{"name":"Department of Pathology, New York University Medical Center, New York, NY, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8663-7787","authenticated-orcid":false,"given":"Kalpana","family":"Ghoshal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8768-9386","authenticated-orcid":false,"given":"W. 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