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Zhao\n et al.<\/jats:italic>\n discovered that mutant\n V. cholerae<\/jats:italic>\n lacking a T6SS could not compete against\n Escherichia coli<\/jats:italic>\n strains in the mouse gut. In contrast, intact\n V. cholerae<\/jats:italic>\n readily gained a foothold in the gut of young mice, pumping up inflammatory immune responses and prompting more violent symptoms.\n <\/jats:p>\n \n Science<\/jats:italic>\n , this issue p.\n 210<\/jats:related-article>\n <\/jats:p>","DOI":"10.1126\/science.aap8775","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T17:40:52Z","timestamp":1516124452000},"page":"210-213","source":"Crossref","is-referenced-by-count":208,"title":["Antagonism toward the intestinal microbiota and its effect on\n Vibrio cholerae<\/i>\n virulence"],"prefix":"10.1126","volume":"359","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5206-7459","authenticated-orcid":true,"given":"Wenjing","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Caro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4786-399X","authenticated-orcid":true,"given":"William","family":"Robins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2792-9293","authenticated-orcid":true,"given":"John J.","family":"Mekalanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10392"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60436-X"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510322103"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10846"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012931107"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.11.001"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004031"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.07.007"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.01.042"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00054-14"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2013.00139"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1012928"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/35020000"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2008.79.708"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1608858113"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.05.004"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06284"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13738"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260064"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.170.6.2575-2583.1988"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1183-784"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.8.3733-3739.1999"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.15.3.704-712.1977"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr1013"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1126\/science.aap8775","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.aap8775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T12:11:44Z","timestamp":1705320704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.aap8775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,12]]},"references-count":25,"journal-issue":{"issue":"6372","published-print":{"date-parts":[[2018,1,12]]}},"alternative-id":["10.1126\/science.aap8775"],"URL":"https:\/\/doi.org\/10.1126\/science.aap8775","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732449549.793558873","asserted-by":"object"}]},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,12]]}}}