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This could have a detrimental impact on fish populations, the fishing industry, and global food availability. Have such impacts occurred before? Yao\n            <jats:italic>et al.<\/jats:italic>\n            report sulfur isotopic data from the Paleocene-Eocene Thermal Maximum, an interval around 55 million years ago when atmospheric carbon dioxide concentrations and global temperatures were also high. They found widespread anoxia and resulting high concentrations of hydrogen sulfide, which is toxic to marine organisms. Similar effects could have severe negative effects on ocean ecosystems.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Science<\/jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6404\" page=\"804\" related-article-type=\"in-this-issue\" vol=\"361\" xlink:href=\"10.1126\/science.aar8658\">804<\/jats:related-article>\n          <\/jats:p>","DOI":"10.1126\/science.aar8658","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T18:06:52Z","timestamp":1532023612000},"page":"804-806","source":"Crossref","is-referenced-by-count":103,"title":["Large-scale ocean deoxygenation during the Paleocene-Eocene Thermal Maximum"],"prefix":"10.1126","volume":"361","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8177-7035","authenticated-orcid":true,"given":"Weiqi","family":"Yao","sequence":"first","affiliation":[{"name":"Department of Earth Sciences, University of Toronto, Toronto, Ontario, M5S 3B1, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adina","family":"Paytan","sequence":"additional","affiliation":[{"name":"Institute of Marine Science, University of California\u2013Santa Cruz, Santa Cruz, CA 95064, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7854-9173","authenticated-orcid":true,"given":"Ulrich G.","family":"Wortmann","sequence":"additional","affiliation":[{"name":"Department of Earth Sciences, University of Toronto, Toronto, Ontario, M5S 3B1, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","unstructured":"F. 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