{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:59:34Z","timestamp":1792061974887,"version":"4.4.0"},"reference-count":83,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6497","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI135995"],"award-info":[{"award-number":["U19 AI135995"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["725422-ReservoirDOCS"],"award-info":[{"award-number":["725422-ReservoirDOCS"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Foundation -- Flanders","award":["G066215N"],"award-info":[{"award-number":["G066215N"]}]},{"name":"Research Foundation -- Flanders","award":["G0D5117N"],"award-info":[{"award-number":["G0D5117N"]}]},{"name":"Research Foundation -- Flanders","award":["G0B9317N"],"award-info":[{"award-number":["G0B9317N"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2020,6,19]]},"abstract":"<jats:title>Older origins of measles virus<\/jats:title>\n                  <jats:p>\n                    Animal domestication by humans is thought to have given many pathogens an opportunity to invade a new host, and measles is one example of this. However, there is controversy about when measles emerged in humans, because the historical descriptions of measles are relatively recent (late ninth century CE). The controversy has persisted in part because ancient RNA is thought to be a poor target for molecular clock techniques. D\u00fcx\n                    <jats:italic>et al.<\/jats:italic>\n                    have overcome the ancient RNA challenge by sequencing a measles virus genome obtained from a museum specimen of the lungs of child who died in 1912 (see the Perspective by Ho and Duch\u00eane). The authors used these and other more recent sequencing data in a Bayesian molecular clock\u2013modeling technique, which showed that measles virus diverged from rinderpest virus in the sixth century BCE, indicating an early origin for measles possibly associated with the beginnings of urbanization.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6497\" page=\"1367\" related-article-type=\"in-this-issue\" vol=\"368\" xlink:href=\"10.1126\/science.aba9411\">1367<\/jats:related-article>\n                    ; see also p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6497\" page=\"1310\" related-article-type=\"in-this-issue\" vol=\"368\" xlink:href=\"10.1126\/science.abc5746\">1310<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.aba9411","type":"journal-article","created":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T19:09:53Z","timestamp":1592507393000},"page":"1367-1370","source":"Crossref","is-referenced-by-count":153,"title":["Measles virus and rinderpest virus divergence dated to the sixth century BCE"],"prefix":"10.1126","volume":"368","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1819-8556","authenticated-orcid":true,"given":"Ariane","family":"D\u00fcx","sequence":"first","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3140-0651","authenticated-orcid":true,"given":"Sebastian","family":"Lequime","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Evolutionary Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute, Katholieke Universiteit (KU) Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3978-3607","authenticated-orcid":true,"given":"Livia Victoria","family":"Patrono","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6547-5283","authenticated-orcid":true,"given":"Bram","family":"Vrancken","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Evolutionary Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute, Katholieke Universiteit (KU) Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seng\u00fcl","family":"Boral","sequence":"additional","affiliation":[{"name":"Institute for Pathology, Charit\u00e9, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1889-4113","authenticated-orcid":true,"given":"Jan F.","family":"Gogarten","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1753-1863","authenticated-orcid":true,"given":"Antonia","family":"Hilbig","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4755-5743","authenticated-orcid":true,"given":"David","family":"Horst","sequence":"additional","affiliation":[{"name":"Institute for Pathology, Charit\u00e9, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Merkel","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2807-7662","authenticated-orcid":true,"given":"Baptiste","family":"Prepoint","sequence":"additional","affiliation":[{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"D\u00e9partement de Biologie, Ecole Normale Sup\u00e9rieure, PSL Universit\u00e9 Paris, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Santibanez","sequence":"additional","affiliation":[{"name":"National Reference Centre for Measles, Mumps, and Rubella, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4579-2315","authenticated-orcid":true,"given":"Jasmin","family":"Schlotterbeck","sequence":"additional","affiliation":[{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9818-479X","authenticated-orcid":true,"given":"Marc A.","family":"Suchard","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA."},{"name":"Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA."},{"name":"Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Ulrich","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navena","family":"Widulin","sequence":"additional","affiliation":[{"name":"Berlin Museum of Medical History, Charit\u00e9, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Mankertz","sequence":"additional","affiliation":[{"name":"National Reference Centre for Measles, Mumps, and Rubella, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2169-7375","authenticated-orcid":true,"given":"Fabian H.","family":"Leendertz","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Harper","sequence":"additional","affiliation":[{"name":"Department of Classics and Letters, University of Oklahoma, Norman, OK, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schnalke","sequence":"additional","affiliation":[{"name":"Berlin Museum of Medical History, Charit\u00e9, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2826-5353","authenticated-orcid":true,"given":"Philippe","family":"Lemey","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Evolutionary Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute, Katholieke Universiteit (KU) Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4834-0509","authenticated-orcid":true,"given":"S\u00e9bastien","family":"Calvignac-Spencer","sequence":"additional","affiliation":[{"name":"Epidemiology of Highly Pathogenic Microorganisms Project Group, Robert Koch Institute, Berlin, Germany."},{"name":"Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","first-page":"224","article-title":"Medical importance of measles","volume":"103","author":"Langmuir A. D.","year":"1962","unstructured":"A. D. Langmuir, Medical importance of measles. Am. J. Dis. Child. 103, 224\u2013226 (1962). 14462174","journal-title":"Am. J. Dis. Child."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31463-0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","unstructured":"A. Dabbagh R. L. Laws C. Steulet L. Dumolard M. N. Mulders K. Kretsinger J. P. Alexander P. A. Rota J. L. Goodson Progress toward regional measles elimination\u2014Worldwide 2000\u20132017. MMWR Morb. Mortal. Wkly. Rep . 67 1323 (2018).","DOI":"10.15585\/mmwr.mm6747a6"},{"key":"e_1_3_2_5_2","unstructured":"WHO Provisional data based on monthly data reported to WHO (Geneva) as of January 2020; www.who.int\/immunization\/monitoring_surveillance\/burden\/vpd\/surveillance_type\/active\/measles_monthlydata\/en"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2012.0139"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05775"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-7-52"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msr170"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2012.140684"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep11648"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msz094"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13450"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00593-16"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0097-z"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1804921115"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","unstructured":"O. Smith M. T. Gilbert Ancient RNA in Paleogenomics: Genome-Scale Analysis of Ancient DNA C. Lindqvist O. P. Rajora Eds. (Springer 2019).","DOI":"10.1007\/13836_2018_17"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000537"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(199907)58:3<313::AID-JMV19>3.0.CO;2-P"},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","unstructured":"R. Kim-Farley Measles in The Cambridge World History of Human Disease K. F. Kiple Ed. (Cambridge Univ. Press 1993).","DOI":"10.1017\/CHOL9780521332866.150"},{"key":"e_1_3_2_21_2","unstructured":"K. R. L. Gupta (translator) Madhava Nidana: Ayurvedic System of Pathology (Sri Satguru Publications 1987)."},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(03)00091-6"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.2307\/2342553"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(66)90161-5"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5296.65"},{"key":"e_1_3_2_26_2","unstructured":"A. D. Cliff P. Haggett M. Smallman-Raynor Measles: An Historical Geography of a Major Human Viral Disease: From Global Expansion to Local Retreat 1840\u20131990 (Blackwell 1993)."},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1017\/ssh.2015.50"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1162\/JINH_a_00794"},{"key":"e_1_3_2_29_2","doi-asserted-by":"crossref","unstructured":"C. A. Spinage Cattle Plague: A History (Springer 2003).","DOI":"10.1007\/978-1-4419-8901-7"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1208124"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.10.061"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006750"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.36666"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000166"},{"key":"e_1_3_2_35_2","doi-asserted-by":"crossref","unstructured":"I. Morris The Measure of Civilization: How Social Development Decides the Fate of Nations (Princeton Univ. Press 2013).","DOI":"10.1515\/9781400844760"},{"key":"e_1_3_2_36_2","unstructured":"S. Lequime slequime\/measles-history: Publication. Zenodo (2020); doi: 10.5281\/zenodo.3764907."},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.213959.116"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_3_2_41_2","unstructured":"G. J\u00e4ger ClipAndMerge; https:\/\/github.com\/apeltzer\/ClipAndMerge."},{"key":"e_1_3_2_42_2","unstructured":"Broad Institute Picard; http:\/\/broadinstitute.github.io\/picard."},{"key":"e_1_3_2_43_2","unstructured":"A. Peltzer DeDup; https:\/\/github.com\/apeltzer\/DeDup."},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt193"},{"key":"e_1_3_2_45_2","unstructured":"Geneious 11.1.5; www.geneious.com."},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-83-6-1419"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-011-0630-8"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vev003"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vew007"},{"key":"e_1_3_2_52_2","article-title":"Bayesian evaluation of temporal signal in measurably evolving populations","author":"Duchene S.","year":"2019","unstructured":"S. Duchene, T. Stadler, S. Y. Ho, D. A. Duchene, V. Dhanasekaran, G. Baele, Bayesian evaluation of temporal signal in measurably evolving populations. bioRxiv 810697 [Preprint] (21 October 2019).","journal-title":"bioRxiv"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1055-7903(02)00326-3"},{"key":"e_1_3_2_54_2","doi-asserted-by":"crossref","unstructured":"X. Xia P. Lemey Assessing substitution saturation with DAMBE in The Phylogenetic Handbook: A Practical Approach to DNA and Protein Phylogeny P. Lemey M. Salemi A. M. Vandamme Eds. (Cambridge Univ. Press 2009).","DOI":"10.1017\/CBO9780511819049"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vey016"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syy032"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1111\/2041-210X.12299"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syz020"},{"key":"e_1_3_2_59_2","first-page":"725","article-title":"A codon-based model of nucleotide substitution for protein-coding DNA sequences","volume":"11","author":"Goldman N.","year":"1994","unstructured":"N. Goldman, Z. Yang, A codon-based model of nucleotide substitution for protein-coding DNA sequences. Mol. Biol. Evol. 11, 725\u2013736 (1994). 7968486","journal-title":"Mol. Biol. Evol."},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026389"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003505"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.2.1265-1271.1997"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_3_2_64_2","unstructured":"H. Li seqtk; https:\/\/github.com\/lh3\/seqtk."},{"key":"e_1_3_2_65_2","unstructured":"T. Chandler Four Thousand Years of Urban Growth: An Historical Census (Mellen 1987)."},{"key":"e_1_3_2_66_2","unstructured":"G. Modelski World Cities: \u20133000 to 2000 (Faros2000 2003)."},{"key":"e_1_3_2_67_2","unstructured":"P. Bairoch Cities and Economic Development: From the Dawn of History to the Present (Univ. Chicago Press 1988)."},{"key":"e_1_3_2_68_2","unstructured":"D. Pasciuti C. Chase-Dunn Estimating the population sizes of cities; https:\/\/irows.ucr.edu\/research\/citemp\/estcit\/estcit.htm."},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12674"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2014.02.013"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2005.02.001"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(08)60344-9"},{"key":"e_1_3_2_73_2","unstructured":"W. H. McNeill Plagues and Peoples . (Anchor Press 1976)."},{"key":"e_1_3_2_74_2","doi-asserted-by":"crossref","unstructured":"P.-P. Patoret K. Yamanouchi U. Mueller-Doblies M. M. Rweyemamu M. Horzinek T. Barrett Rinderpest\u2014An old and worldwide story: history to c.1902 in Rinderpest and Peste des Petits Ruminants: Virus Plagues of Large and Small Ruminants T. Barrett P.-P. Pastoret W. Taylor Eds. (Elsevier 2005).","DOI":"10.1016\/B978-012088385-1\/50035-6"},{"key":"e_1_3_2_75_2","doi-asserted-by":"crossref","unstructured":"J. Blancou Old prophylactic methods in Rinderpest and Peste des Petits Ruminants: Virus Plagues of Large and Small Ruminants T. Barrett P.-P. Pastoret W. Taylor Eds. (Elsevier 2005).","DOI":"10.1016\/B978-012088385-1\/50039-3"},{"key":"e_1_3_2_76_2","unstructured":"OIE Peste des Petits Ruminants; www.oie.int\/fileadmin\/Home\/eng\/Animal_Health_in_the_World\/docs\/pdf\/Disease_cards\/PESTE_DES_PETITS_RUMINANTS.pdf."},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1188836"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1912.130973"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2019.02.011"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1796"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02206-0"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2011.0223"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-81-8-1927"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay6485"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1126\/science.aba9411","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.aba9411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T19:07:09Z","timestamp":1705345629000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.aba9411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,19]]},"references-count":83,"journal-issue":{"issue":"6497","published-print":{"date-parts":[[2020,6,19]]}},"alternative-id":["10.1126\/science.aba9411"],"URL":"https:\/\/doi.org\/10.1126\/science.aba9411","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,19]]}}}