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Some of these are neutralizing, meaning that they prevent the virus from being infectious, and can thus be used to treat viral diseases. Wu\n                    <jats:italic>et al.<\/jats:italic>\n                    isolated four neutralizing antibodies from a convalescent coronavirus disease 2019 (COVID-19) patient. Two of the antibodies, B38 and H4, blocked the receptor binding domain (RBD) of the viral spike protein from binding to the cellular receptor, angiotensin-converting enzyme 2 (ACE2). The structure of the RBD bound to B38 shows that the B38-binding site overlaps with the binding site for ACE2. Although H4 also blocks RBD binding to ACE2, it binds at a different site, and thus the two antibodies can bind simultaneously. This pair of antibodies could potentially be used together in clinical applications.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6496\" page=\"1274\" related-article-type=\"in-this-issue\" vol=\"368\" xlink:href=\"10.1126\/science.abc2241\">1274<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.abc2241","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T15:11:22Z","timestamp":1589382682000},"page":"1274-1278","source":"Crossref","is-referenced-by-count":1002,"title":["A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2"],"prefix":"10.1126","volume":"368","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2734-0673","authenticated-orcid":true,"given":"Yan","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pathogen Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China."},{"name":"Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4568-9158","authenticated-orcid":true,"given":"Feiran","family":"Wang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China."},{"name":"School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8607-3750","authenticated-orcid":true,"given":"Chenguang","family":"Shen","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China."},{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People\u2019s Hospital, Shenzhen, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7069-9556","authenticated-orcid":true,"given":"Weiyu","family":"Peng","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China."},{"name":"College of Veterinary Medicine, China Agricultural University, Beijing, 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