{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:09:00Z","timestamp":1791443340109,"version":"4.3.3"},"reference-count":17,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6505","license":[{"start":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T00:00:00Z","timestamp":1597363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National key research and development project of China","award":["2016YFD0500304"],"award-info":[{"award-number":["2016YFD0500304"]}]},{"name":"National Mega projects of China for Major Infectious Diseases","award":["2017ZX10304402"],"award-info":[{"award-number":["2017ZX10304402"]}]},{"name":"CAMS Initiative for Innovative Medicine of China","award":["2016-I2M-2-006"],"award-info":[{"award-number":["2016-I2M-2-006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2020,8,14]]},"abstract":"Immunity from reinfection<\/jats:title>\n \n One of the many open questions about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is whether an individual who has cleared the virus can be infected a second time and get sick. Chandrashekar\n et al.<\/jats:italic>\n and Deng\n et al.<\/jats:italic>\n generated rhesus macaque models of SARS-CoV-2 infection and tested whether natural SARS-CoV-2 infection could result in immunity to viral rechallenge. They found that animals indeed developed immune responses that protected against a second infection. Although there are differences between SARS-CoV-2 infection in macaques and in humans, these findings have key implications for public health and economic initiatives if validated in human studies.\n <\/jats:p>\n \n Science<\/jats:italic>\n , this issue p.\n 812<\/jats:related-article>\n , p.\n 818<\/jats:related-article>\n <\/jats:p>","DOI":"10.1126\/science.abc5343","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T19:05:38Z","timestamp":1593716738000},"page":"818-823","source":"Crossref","is-referenced-by-count":425,"title":["Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques"],"prefix":"10.1126","volume":"369","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1619-2313","authenticated-orcid":true,"given":"Wei","family":"Deng","sequence":"first","affiliation":[{"name":"Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, NHC Key Laboratory of Human Disease Comparative Medicine, 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