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Several narratives have been propagated by social media and, in some cases, national policies were forged in response. Now that many thousands of virus sequences are available, two studies analyzed some of the key early events in the spread of SARS-CoV-2. Bedford\n            <jats:italic>et al.<\/jats:italic>\n            found that the virus arrived in Washington state in late January or early February. The viral genome from the first case detected had mutations similar to those found in Chinese samples and rapidly spread and dominated subsequent undetected community transmission. The other viruses detected had origins in Europe. Worobey\n            <jats:italic>et al.<\/jats:italic>\n            found that early introductions into Germany and the west coast of the United States were extinguished by vigorous public health efforts, but these successes were largely unrecognized. Unfortunately, several major travel events occurred in February, including repatriations from China, with lax public health follow-up. Serial, independent introductions triggered the major outbreaks in the United States and Europe that still hold us in the grip of control measures.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Science<\/jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6516\" page=\"571\" related-article-type=\"in-this-issue\" vol=\"370\" xlink:href=\"10.1126\/science.abc0523\">571<\/jats:related-article>\n            , p.\n            <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6516\" page=\"564\" related-article-type=\"in-this-issue\" vol=\"370\" xlink:href=\"10.1126\/science.abc8169\">564<\/jats:related-article>\n          <\/jats:p>","DOI":"10.1126\/science.abc8169","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T23:12:10Z","timestamp":1599779530000},"page":"564-570","source":"Crossref","is-referenced-by-count":364,"title":["The emergence of SARS-CoV-2 in Europe and North America"],"prefix":"10.1126","volume":"370","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3578-1367","authenticated-orcid":true,"given":"Michael","family":"Worobey","sequence":"first","affiliation":[{"name":"Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0977-2886","authenticated-orcid":true,"given":"Jonathan","family":"Pekar","sequence":"additional","affiliation":[{"name":"Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, CA 92093, USA."},{"name":"Department of Biomedical Informatics, University of California San Diego, La Jolla, CA 92093, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3136-2218","authenticated-orcid":true,"given":"Brendan B.","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4814-0179","authenticated-orcid":true,"given":"Martha I.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verity","family":"Hill","sequence":"additional","affiliation":[{"name":"Institute of Evolutionary Biology, University of Edinburgh, King\u2019s Buildings, Edinburgh EH9 3FL, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey B.","family":"Joy","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, BC, Canada."},{"name":"BC Centre for Excellence in HIV\/AIDS, Vancouver, BC, Canada."},{"name":"Bioinformatics Programme, University of British Columbia, Vancouver, BC, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4337-3707","authenticated-orcid":true,"given":"Andrew","family":"Rambaut","sequence":"additional","affiliation":[{"name":"Institute of Evolutionary Biology, University of Edinburgh, King\u2019s Buildings, Edinburgh EH9 3FL, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9818-479X","authenticated-orcid":true,"given":"Marc A.","family":"Suchard","sequence":"additional","affiliation":[{"name":"Department of Biomathematics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA."},{"name":"Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA 90095, USA."},{"name":"Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4882-5856","authenticated-orcid":true,"given":"Joel O.","family":"Wertheim","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2826-5353","authenticated-orcid":true,"given":"Philippe","family":"Lemey","sequence":"additional","affiliation":[{"name":"KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_3_2_2","unstructured":"Trevor Bedford (@trvrb) \u201cThe team at the @seattleflustudy have sequenced the genome the #COVID19 community case reported yesterday from Snohomish County WA and have posted the sequence publicly to gisaid.org. There are some enormous implications here. 1\/9\u201d Twitter 29 February 2020 11:20 p.m.; https:\/\/twitter.com\/trvrb\/status\/1233970271318503426."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc0523"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.04.021"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc1917"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb9263"},{"key":"e_1_3_3_7_2","unstructured":"Trevor Bedford (@trvrb) \u201cThis separate introduction may have been to British Columbia or may have been elsewhere. Better resolving this introduction geographically would benefit from additional sequencing of samples collected closer in time to the introduction event. 14\/18.\u201d Twitter 25 May 2020 7:35 p.m.; https:\/\/twitter.com\/trvrb\/status\/1265063937663328256."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001191"},{"key":"e_1_3_3_9_2","unstructured":"A. Harmon \u201cInside the Race to Contain America\u2019s First Coronavirus Case.\u201d The New York Times 5 February 2020; www.nytimes.com\/2020\/02\/05\/us\/corona-virus-washington-state.html."},{"key":"e_1_3_3_10_2","unstructured":"D. A. 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