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The key is to find a means of rapidly interconverting the reactants while one of them is being more efficiently funneled to product. DeHovitz\n                    <jats:italic>et al.<\/jats:italic>\n                    report cooperative application of organocatalysis, photoredox catalysis, and enzymatic catalysis to achieve DKR of \u03b2-substituted ketones into chiral alcohols. This \u03b2 position has typically been considered too configurationally stable for a DKR approach.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6507\" page=\"1113\" related-article-type=\"in-this-issue\" vol=\"369\" xlink:href=\"10.1126\/science.abc9909\">1113<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.abc9909","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T17:45:37Z","timestamp":1602870337000},"page":"1113-1118","source":"Crossref","is-referenced-by-count":136,"title":["Static to inducibly dynamic stereocontrol: The convergent use of racemic \u03b2-substituted ketones"],"prefix":"10.1126","volume":"369","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9994-6311","authenticated-orcid":true,"given":"Jacob S.","family":"DeHovitz","sequence":"first","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2938-1981","authenticated-orcid":true,"given":"Yong Yao","family":"Loh","sequence":"additional","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob A.","family":"Kautzky","sequence":"additional","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3141-5279","authenticated-orcid":true,"given":"Kazunori","family":"Nagao","sequence":"additional","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Meichan","sequence":"additional","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8681-7924","authenticated-orcid":true,"given":"Motoshi","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Merck Center for Catalysis, Princeton University, Princeton, NJ 08544, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6447-0587","authenticated-orcid":true,"given":"David W. 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