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However, the mechanisms by which these cells can identify and migrate to sites of injury have remained unclear. Using intravital imaging of mouse peritoneal cavities, Zindel\n                    <jats:italic>et al.<\/jats:italic>\n                    report that GATA6\n                    <jats:sup>+<\/jats:sup>\n                    macrophages rapidly assemble clot-like structures in a process strongly analogous to thrombosis (see the Perspective by Herrick and Allen). The formation of these aggregates requires the expression of macrophage scavenger receptor domains and acts to plug wounds and promote healing. This pathway can be inadvertently activated during medical procedures, when macrophage aggregates can promote the generation of abdominal scar tissue known as adhesions. Inhibition of macrophage scavenger receptors may therefore be a useful therapeutic approach after surgeries that cause injury to body cavities.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" related-article-type=\"in-this-issue\" xlink:href=\"10.1126\/science.abe0595\">eabe0595<\/jats:related-article>\n                    ; see also p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6533\" page=\"993\" related-article-type=\"in-this-issue\" vol=\"371\" xlink:href=\"10.1126\/science.abg5416\">993<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.abe0595","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T14:32:03Z","timestamp":1614954723000},"source":"Crossref","is-referenced-by-count":153,"title":["Primordial GATA6 macrophages function as extravascular platelets in sterile injury"],"prefix":"10.1126","volume":"371","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3685-9338","authenticated-orcid":true,"given":"J.","family":"Zindel","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Physiology, University of Calgary, Calgary, Alberta, Canada."},{"name":"Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Department of Visceral Surgery and Medicine, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6195-3866","authenticated-orcid":true,"given":"M.","family":"Peiseler","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Physiology, University of Calgary, Calgary, Alberta, Canada."},{"name":"Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0411-944X","authenticated-orcid":true,"given":"M.","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Physiology, University of Calgary, Calgary, Alberta, Canada."},{"name":"Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3740-8635","authenticated-orcid":true,"given":"C.","family":"Deppermann","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Physiology, University of Calgary, Calgary, Alberta, Canada."},{"name":"Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada."},{"name":"Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4702-8540","authenticated-orcid":true,"given":"W. 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