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With this in mind, Rappazzo\n                    <jats:italic>et al.<\/jats:italic>\n                    isolated antibodies from a survivor of the 2003 severe acute respiratory syndrome coronavirus (SARS-CoV), used yeast display libraries to introduce diversity into these antibodies, and then screened for binding to SARS-CoV-2. One of the affinity-matured progeny strongly neutralized SARS-CoV-2, SARS-CoV, and two SARS-related viruses from bats. In addition, this antibody bound to the receptor-binding domains from a panel of sarbecoviruses, suggesting broader activity, and provided protection against SARS-CoV and SARS-CoV-2 in mouse models.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , this issue p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" issue=\"6531\" page=\"823\" related-article-type=\"in-this-issue\" vol=\"371\" xlink:href=\"10.1126\/science.abf4830\">823<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.abf4830","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T15:10:53Z","timestamp":1611587453000},"page":"823-829","source":"Crossref","is-referenced-by-count":358,"title":["Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody"],"prefix":"10.1126","volume":"371","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8415-444X","authenticated-orcid":true,"given":"C. 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