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Closure of the critical period stabilizes the circuits. Looking at development in the mouse visual cortex, Ribot\n                    <jats:italic>et al.<\/jats:italic>\n                    found that astrocytes increase their expression of the gap junction channel subunit connexin 30, which in turn inhibits expression of a matrix-degrading enzyme (see the Perspective by Kofuji and Araque). As the matrix stabilizes, inhibitory interneurons mature, and the unusual flexibility of the critical period comes to an end.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Science<\/jats:italic>\n                    , abf5273, this issue p.\n                    <jats:related-article issue=\"6550\" page=\"77\" related-article-type=\"in-this-issue\" vol=\"373\">77<\/jats:related-article>\n                    ; see also abj6745, p.\n                    <jats:related-article issue=\"6550\" page=\"29\" related-article-type=\"in-this-issue\" vol=\"373\">29<\/jats:related-article>\n                  <\/jats:p>","DOI":"10.1126\/science.abf5273","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T15:08:34Z","timestamp":1625152114000},"page":"77-81","source":"Crossref","is-referenced-by-count":140,"title":["Astrocytes close the mouse critical period for visual 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