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Treatment strategies that are broadly protective against current and future SARS-like coronaviruses are needed. Martinez\n                    <jats:italic>et al<\/jats:italic>\n                    . take on this challenge by developing vaccines based on chimeras of the viral spike protein. The messenger RNA vaccines encode spike proteins composed of domain modules from epidemic and pandemic coronaviruses, as well as bat coronaviruses with the potential to cross to humans. 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