{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T10:09:57Z","timestamp":1760609397636,"version":"3.41.2"},"reference-count":15,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6561","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2021,9,17]]},"abstract":"<jats:p>\n            Break\n            <jats:italic>et al<\/jats:italic>\n            . (Research Articles, 15 January 2021, eaay5731) conclude that T cell overproduction of interferon-\u03b3 causes chronic mucocutaneous candidiasis (CMC), a typical early feature of autoimmune polyendocrinopathy\u2013candidiasis\u2013ectodermal dystrophy (APECED). This contradicts studies implicating interleukin IL-17 and IL-22 deficiencies as a cause of CMC. We propose that Break\n            <jats:italic>et al<\/jats:italic>\n            . have focused on late-arising events rather than more common primary causes of CMC.\n          <\/jats:p>","DOI":"10.1126\/science.abi6235","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T17:55:58Z","timestamp":1631814958000},"source":"Crossref","is-referenced-by-count":9,"title":["Comment on \u201cAberrant type 1 immunity drives susceptibility to mucosal fungal infections\u201d"],"prefix":"10.1126","volume":"373","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5426-4648","authenticated-orcid":true,"given":"Kai","family":"Kisand","sequence":"first","affiliation":[{"name":"Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Meager","sequence":"additional","affiliation":[{"name":"Regaem Consultants, Whitchurch Gardens, Edgware, Middlesex, UK."},{"name":"Francis Crick Institute, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-5793","authenticated-orcid":true,"given":"Adrian","family":"Hayday","sequence":"additional","affiliation":[{"name":"Regaem Consultants, Whitchurch Gardens, Edgware, Middlesex, UK."},{"name":"Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King\u2019s College London, London, UK."},{"name":"Francis Crick Institute, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Willcox","sequence":"additional","affiliation":[{"name":"Francis Crick Institute, London, UK."},{"name":"Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.06.024"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20091669"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-013-9938-6"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916934.2014.929666"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2017.97"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay5731"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3670"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20130877"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201747209"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050693"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00838"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.88782"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916934.2017.1344972"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.22286"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03262642"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.abi6235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T22:58:11Z","timestamp":1705359491000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.abi6235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,17]]},"references-count":15,"journal-issue":{"issue":"6561","published-print":{"date-parts":[[2021,9,17]]}},"alternative-id":["10.1126\/science.abi6235"],"URL":"https:\/\/doi.org\/10.1126\/science.abi6235","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"type":"print","value":"0036-8075"},{"type":"electronic","value":"1095-9203"}],"subject":[],"published":{"date-parts":[[2021,9,17]]},"article-number":"eabi6235"}}