{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:34:35Z","timestamp":1792614875352,"version":"4.5.0"},"reference-count":50,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6596","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2022,5,27]]},"abstract":"<jats:p>Temporary postoperative cardiac pacing requires devices with percutaneous leads and external wired power and control systems. This hardware introduces risks for infection, limitations on patient mobility, and requirements for surgical extraction procedures. Bioresorbable pacemakers mitigate some of these disadvantages, but they demand pairing with external, wired systems and secondary mechanisms for control. We present a transient closed-loop system that combines a time-synchronized, wireless network of skin-integrated devices with an advanced bioresorbable pacemaker to control cardiac rhythms, track cardiopulmonary status, provide multihaptic feedback, and enable transient operation with minimal patient burden. The result provides a range of autonomous, rate-adaptive cardiac pacing capabilities, as demonstrated in rat, canine, and human heart studies. This work establishes an engineering framework for closed-loop temporary electrotherapy using wirelessly linked, body-integrated bioelectronic devices.<\/jats:p>","DOI":"10.1126\/science.abm1703","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T17:57:34Z","timestamp":1653587854000},"page":"1006-1012","source":"Crossref","is-referenced-by-count":272,"title":["A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy"],"prefix":"10.1126","volume":"376","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3813-3442","authenticated-orcid":true,"given":"Yeon Sik","family":"Choi","sequence":"first","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Precision Biology Research Center, Sungkyunkwan University, Suwon 16419, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1808-7824","authenticated-orcid":true,"given":"Hyoyoung","family":"Jeong","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5887-9212","authenticated-orcid":true,"given":"Rose T.","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raudel","family":"Avila","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7812-0860","authenticated-orcid":true,"given":"Anna","family":"Pfenniger","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0934-4718","authenticated-orcid":true,"given":"Jaeyoung","family":"Yoo","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1626-7669","authenticated-orcid":true,"given":"Jong Yoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Sibel Health, Niles, IL 60714, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0750-5007","authenticated-orcid":true,"given":"Andreas","family":"Tzavelis","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Medical Scientist Training Program, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2096-2261","authenticated-orcid":true,"given":"Young Joong","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8278-3517","authenticated-orcid":true,"given":"Sheena W.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The George Washington University, Washington, DC 20052, USA."},{"name":"Department of Cardiothoracic Surgery, Veteran Affairs Medical Center, Washington, DC 20422, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2129-0401","authenticated-orcid":true,"given":"Helen S.","family":"Knight","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7375-4821","authenticated-orcid":true,"given":"Seungyeob","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Electronic Engineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 406-772, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5441-1054","authenticated-orcid":true,"given":"Hak-Young","family":"Ahn","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Precision Biology Research Center, Sungkyunkwan University, Suwon 16419, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1561-8009","authenticated-orcid":true,"given":"Grace","family":"Wickerson","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0648-5921","authenticated-orcid":true,"given":"Abraham","family":"V\u00e1zquez-Guardado","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4122-7565","authenticated-orcid":true,"given":"Elizabeth","family":"Higbee-Dempsey","sequence":"additional","affiliation":[{"name":"Developmental Therapeutics Core, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4232-1342","authenticated-orcid":true,"given":"Bender A.","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0835-6453","authenticated-orcid":true,"given":"Michael A.","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The George Washington University, Washington, DC 20052, USA."},{"name":"Department of Cardiothoracic Surgery, Veteran Affairs Medical Center, Washington, DC 20422, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Holleran","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The George Washington University, Washington, DC 20052, USA."},{"name":"Department of Cardiothoracic Surgery, Veteran Affairs Medical Center, Washington, DC 20422, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3097-6974","authenticated-orcid":true,"given":"Leen Abdul","family":"Razzak","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7183-6839","authenticated-orcid":true,"given":"Alana N.","family":"Miniovich","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geumbee","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2440-1584","authenticated-orcid":true,"given":"Beth","family":"Geist","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8174-3214","authenticated-orcid":true,"given":"Brandon","family":"Kim","sequence":"additional","affiliation":[{"name":"Sibel Health, Niles, IL 60714, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuling","family":"Han","sequence":"additional","affiliation":[{"name":"Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."},{"name":"Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-546X","authenticated-orcid":true,"given":"Jaclyn A.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9898-1462","authenticated-orcid":true,"given":"Kedar","family":"Aras","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2625-2471","authenticated-orcid":true,"given":"Sung Soo","family":"Kwak","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0294-9565","authenticated-orcid":true,"given":"Joohee","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3479-6054","authenticated-orcid":true,"given":"Emily Alexandria","family":"Waters","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6099-1374","authenticated-orcid":true,"given":"Xiangxing","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, TX 78712, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Burrell","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5695-5816","authenticated-orcid":true,"given":"Keum","family":"San Chun","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, TX 78712, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4308-389X","authenticated-orcid":true,"given":"Claire","family":"Liu","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changsheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Y.","family":"Rwei","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7461-7543","authenticated-orcid":true,"given":"Alisha N.","family":"Spann","sequence":"additional","affiliation":[{"name":"Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0509-0370","authenticated-orcid":true,"given":"Anthony","family":"Banks","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9033-9590","authenticated-orcid":true,"given":"David","family":"Johnson","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6469-5778","authenticated-orcid":true,"given":"Zheng Jenny","family":"Zhang","sequence":"additional","affiliation":[{"name":"Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."},{"name":"Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5981-2925","authenticated-orcid":true,"given":"Chad R.","family":"Haney","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1799-7743","authenticated-orcid":true,"given":"Sung Hun","family":"Jin","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Electronic Engineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 406-772, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3090-0328","authenticated-orcid":true,"given":"Alan Varteres","family":"Sahakian","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Electrical and Computer Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0483-8359","authenticated-orcid":true,"given":"Yonggang","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Precision Biology Research Center, Sungkyunkwan University, Suwon 16419, Republic of Korea."},{"name":"Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2403-905X","authenticated-orcid":true,"given":"Gregory D.","family":"Trachiotis","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Veteran Affairs Medical Center, Washington, DC 20422, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley P.","family":"Knight","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi K.","family":"Arora","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Cardiology, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1483-5039","authenticated-orcid":true,"given":"Igor R.","family":"Efimov","sequence":"additional","affiliation":[{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3830-5980","authenticated-orcid":true,"given":"John A.","family":"Rogers","sequence":"additional","affiliation":[{"name":"Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA."},{"name":"Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.919704"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2005.01672.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0823-6"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)90505-7"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.64.5.604"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X8501300109"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00454.x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.173328"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.987354"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-021-00948-x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19660-6"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abb1093"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1557\/mrs.2020.25"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202000941"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature16492"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1226325"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12461"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-82"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0792-9"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1687-0"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abg3092"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2019786117"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025972"},{"key":"e_1_3_3_25_2","unstructured":"Institute of Electrical and Electronics Engineers (IEEE) \u201cIEEE standard for safety levels with respect to human exposure to radio frequency electromagnetic fields 3 kHz to 300 GHz\u201d in IEEE Std C95.1-2005 (Revision IEEE Std C95.1-1991) (IEEE 2006) pp. 1\u2013238."},{"key":"e_1_3_3_26_2","unstructured":"Optocardiography Code for analysis of optical mapping data (2018); https:\/\/github.com\/optocardiography\/RHYTHM-2.0."},{"key":"e_1_3_3_27_2","unstructured":"Optocardiography Code for Masson\u2019s trichrome quantification (2021); https:\/\/github.com\/optocardiography\/massonstrichromequantification."},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0270(97)00160-X"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/mi8120359"},{"key":"e_1_3_3_30_2","unstructured":"S. F. Pichorim in Proceedings of the14th International Symposium on Biotelemetry M. R. Neuman T. Penzel S. Salmons Eds. (Tectum Verlag Marburg 1998) pp. 71\u201377."},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143254"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau0780"},{"key":"e_1_3_3_33_2","unstructured":"U.S. Food and Drug Administration (FDA) \u201cTesting and labeling medical devices for safety in the magnetic resonance (MR) environment: Guidance for industry and Food and Drug Administration staff\u201d (FDA 2021); https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/testing-and-labeling-medical-devices-safety-magnetic-resonance-mr-environment."},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202102724"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-021-01051-x"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2020.08.021"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00120-3"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2011.00477.x"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.3.1159"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1990.tb02026.x"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.3.903"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.71.5.937"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-12-200112180-00010"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl503997m"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1557\/mrs.2020.24"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8651(05)70131-4"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun024"},{"key":"e_1_3_3_48_2","first-page":"137","article-title":"Sensors for rate responsive pacing","volume":"4","author":"Dell\u2019Orto S.","year":"2004","unstructured":"S. Dell\u2019Orto, P. Valli, E. M. Greco, Sensors for rate responsive pacing. Indian Pacing Electrophysiol. J. 4, 137\u2013145 (2004). 16943981","journal-title":"Indian Pacing Electrophysiol. J."},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2012.03445.x"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur419"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-020-00445-9"}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.abm1703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:14:58Z","timestamp":1705364098000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.abm1703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,27]]},"references-count":50,"journal-issue":{"issue":"6596","published-print":{"date-parts":[[2022,5,27]]}},"alternative-id":["10.1126\/science.abm1703"],"URL":"https:\/\/doi.org\/10.1126\/science.abm1703","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,27]]}}}