{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:20:43Z","timestamp":1790500843552,"version":"4.1.0"},"reference-count":17,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6646","content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Science"],"published-print":{"date-parts":[[2023,5,19]]},"abstract":"<jats:p>The use of hands for gathering rich sensory information is essential for proper interaction with the environment; therefore, the restoration of sensation is critical for reestablishing the sense of embodiment in hand amputees. Here, we show that a noninvasive wearable device can be used to provide thermal sensations on amputees\u2019 phantom hands. The device delivers thermal stimuli to specific regions of skin on their residual limb. These sensations were phenomenologically similar to those on the intact limbs and were stable over time. Using the device, the subjects could successfully exploit the thermal phantom hand maps to detect and discriminate different thermal stimuli. The use of a wearable device that provides thermal sensation can increase the sense of embodiment and improve life quality in hand amputees.<\/jats:p>","DOI":"10.1126\/science.adf6121","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:58:45Z","timestamp":1684418325000},"page":"731-735","update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":66,"title":["Restoration of natural thermal sensation in upper-limb amputees"],"prefix":"10.1126","volume":"380","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4365-5328","authenticated-orcid":true,"given":"Francesco","family":"Iberite","sequence":"first","affiliation":[{"name":"The BioRobotics Institute, Health Interdisciplinary Center, and Department of Excellence in Robotics and AI, Scuola Superiore Sant\u2019Anna, 56127 Pisa, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3698-5879","authenticated-orcid":true,"given":"Jonathan","family":"Muheim","sequence":"additional","affiliation":[{"name":"Bertarelli Foundation Chair in Translational Neural Engineering, Neuro-X Institute, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, 1015 Lausanne, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9436-294X","authenticated-orcid":true,"given":"Outman","family":"Akouissi","sequence":"additional","affiliation":[{"name":"Bertarelli Foundation Chair in Translational Neural Engineering, Neuro-X Institute, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, 1015 Lausanne, Switzerland."},{"name":"Bertarelli Foundation Chair in Neuroprosthetic Technology, Neuro-X Institute, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, 1015 Lausanne, 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