{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:32:42Z","timestamp":1792045962688,"version":"4.4.0"},"reference-count":48,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6687","content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Science"],"published-print":{"date-parts":[[2024,3,8]]},"abstract":"<jats:p>\n                    Phonation critically depends on precise controls of laryngeal muscles in coordination with ongoing respiration. However, the neural mechanisms governing these processes remain unclear. We identified excitatory vocalization-specific laryngeal premotor neurons located in the retroambiguus nucleus (RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    ) in adult mice as being both necessary and sufficient for driving vocal cord closure and eliciting mouse ultrasonic vocalizations (USVs). The duration of RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    activation can determine the lengths of both USV syllables and concurrent expiration periods, with the impact of RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    activation depending on respiration phases. RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    neurons receive inhibition from the preB\u00f6tzinger complex, and inspiration needs override RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    -mediated vocal cord closure. Ablating inhibitory synapses in RAm\n                    <jats:sup>VOC<\/jats:sup>\n                    neurons compromised this inspiration gating of laryngeal adduction, resulting in discoordination of vocalization with respiration. Our study reveals the circuits for vocal production and vocal-respiratory coordination.\n                  <\/jats:p>","DOI":"10.1126\/science.adi8081","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T13:59:04Z","timestamp":1709819944000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":63,"title":["Brainstem control of vocalization and its coordination with respiration"],"prefix":"10.1126","volume":"383","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3189-3830","authenticated-orcid":true,"given":"Jaehong","family":"Park","sequence":"first","affiliation":[{"name":"Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."},{"name":"Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seonmi","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0976-7684","authenticated-orcid":true,"given":"Jun","family":"Takatoh","sequence":"additional","affiliation":[{"name":"Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9432-0070","authenticated-orcid":true,"given":"Shengli","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Duke University Medical Center, Durham, NC, 27710, 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