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The microbiota also plays an important role in seeding islet-resident macrophages, and macrophage depletion during development reduces \u03b2 cells.\n            <jats:italic>Candida dubliniensis<\/jats:italic>\n            increases \u03b2 cells in a macrophage-dependent manner through distinctive cell wall composition and reduces murine diabetes incidence. Provision of\n            <jats:italic>C. dubliniensis<\/jats:italic>\n            after \u03b2 cell ablation or antibiotic treatment improves \u03b2 cell function. 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