{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:35:27Z","timestamp":1792607727441,"version":"4.5.0"},"reference-count":72,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6712","content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Science"],"published-print":{"date-parts":[[2024,8,30]]},"abstract":"<jats:p>Recent respiratory outbreaks have garnered substantial attention, yet most respiratory monitoring remains confined to physical signals. Exhaled breath condensate (EBC) harbors rich molecular information that could unveil diverse insights into an individual\u2019s health. Unfortunately, challenges related to sample collection and the lack of on-site analytical tools impede the widespread adoption of EBC analysis. Here, we introduce EBCare, a mask-based device for real-time in situ monitoring of EBC biomarkers. Using a tandem cooling strategy, automated microfluidics, highly selective electrochemical biosensors, and a wireless reading circuit, EBCare enables continuous multimodal monitoring of EBC analytes across real-life indoor and outdoor activities. We validated EBCare\u2019s usability in assessing metabolic conditions and respiratory airway inflammation in healthy participants, patients with chronic obstructive pulmonary disease or asthma, and patients after COVID-19 infection.<\/jats:p>","DOI":"10.1126\/science.adn6471","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T13:59:22Z","timestamp":1724939962000},"page":"954-961","update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":220,"title":["A smart mask for exhaled breath condensate harvesting and analysis"],"prefix":"10.1126","volume":"385","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5278-0727","authenticated-orcid":true,"given":"Wenzheng","family":"Heng","sequence":"first","affiliation":[{"name":"Andrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, 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we require de-aeration of exhaled breath condensate samples for measuring pH","volume":"56","author":"De S.","year":"2020","unstructured":"S. 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