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We demonstrate that flowing CO\n                    <jats:sub>2<\/jats:sub>\n                    gas into an acid bubbler\u2014which carries trace amounts of acid vapor into a gas diffusion electrode for silver-catalyzed CO\n                    <jats:sub>2<\/jats:sub>\n                    RR to carbon monoxide (CO)\u2014can prevent salt accumulation. In a 100-square-centimeter, scaled-up CO\n                    <jats:sub>2<\/jats:sub>\n                    RR membrane electrode assembly electrolyzer with single serpentine flow channels, the acid humidification method achieved the 4500 hours of stability milestone at 100 mA cm\n                    <jats:sup>\u22122<\/jats:sup>\n                    without compromising the CO faradaic efficiency, whereas a conventional water-humidified CO\n                    <jats:sub>2<\/jats:sub>\n                    feed only operated stably for ~80 hours. The acid-humidified CO\n                    <jats:sub>2<\/jats:sub>\n                    approach was extended to bismuth, copper, and zinc catalysts.\n                  <\/jats:p>","DOI":"10.1126\/science.adr3834","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T11:30:37Z","timestamp":1750246237000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":199,"title":["Acid-humidified CO\n                    <sub>2<\/sub>\n                    gas input for stable electrochemical CO\n                    <sub>2<\/sub>\n                    reduction reaction"],"prefix":"10.1126","volume":"388","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-518X","authenticated-orcid":true,"given":"Shaoyun","family":"Hao","sequence":"first","affiliation":[{"name":"Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX, 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