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In this study, we compared skin colonization by\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    versus\n                    <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                    to illuminate distinct fungal-immune interactions in mice.\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    exhibited enhanced skin persistence, hair follicle tropism, and direct hair binding. Whereas\n                    <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                    triggered a type 3\/17\u2013skewed sterilizing antifungal immune response,\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    triggered a type 1 interferon-\u03b3 (IFN\u03b3)\u2013driven response directed toward hair follicles. IFN\u03b3 enhanced\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    colonization by signaling to keratinocytes and repressing epithelial antifungal defense programs. Genetic and biochemical approaches demonstrated that, in response to cues associated with the skin,\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    increases cell wall chitin exposure, triggering type 1 immunity and promoting fungal persistence.\n                  <\/jats:p>","DOI":"10.1126\/science.adu6688","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:00:38Z","timestamp":1786039238000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":5,"title":["The fungal pathogen\n                    <i>Candida auris<\/i>\n                    exposes chitin to trigger IFN\u03b3 and persist in hair follicles"],"prefix":"10.1126","volume":"393","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7175-5046","authenticated-orcid":true,"given":"Eric Dean","family":"Merrill","sequence":"first","affiliation":[{"name":"Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA."},{"name":"Department of Dermatology, Veterans Affairs Medical Center, San Francisco, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8697-0179","authenticated-orcid":true,"given":"Victoria","family":"Prudent","sequence":"additional","affiliation":[{"name":"Department of Microbiology &amp; 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