{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:05:08Z","timestamp":1787951108818,"version":"build-2784847793"},"reference-count":100,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6792","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31790410"],"award-info":[{"award-number":["31790410"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National pig industry technology system","award":["CARS-35"],"award-info":[{"award-number":["CARS-35"]}]},{"name":"Key science and technology development program of Jiangxi Province","award":["20213AAF01010"],"award-info":[{"award-number":["20213AAF01010"]}]}],"content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Science"],"published-print":{"date-parts":[[2026,3,26]]},"abstract":"<jats:p>\n                    Although massive cell atlases are already available, it is still a challenge to obtain an atlas of all tissues within a single body, especially in fetuses and pregnant mothers. We present a transcriptomic atlas of 2.56 million single cells covering 115 and 119 tissues from one fetal pig and its pregnant mother, respectively. We found that a cluster of heart capillary endothelial cells with enhanced fatty acid transit capability was enriched for pregnancy but restored after gestation. We also deciphered that\n                    <jats:sc>l<\/jats:sc>\n                    -leucine transport insufficiency in the trophoblast causes fetal growth restriction by reducing a muscle type II myofiber subcluster. Our \u201call-from-one\u201d strategy enabled the identification of tissue cell type\u2013specific transcription factors and provided insights into pregnancy heart adaptation and fetal growth restriction.\n                  <\/jats:p>","DOI":"10.1126\/science.adu7265","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T18:00:46Z","timestamp":1774548046000},"update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Family single-cell atlases reveal pig pregnancy and fetal growth restriction critical cell types"],"prefix":"10.1126","volume":"391","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9755-5230","authenticated-orcid":true,"given":"Liping","family":"Cai","sequence":"first","affiliation":[{"name":"National Key Laboratory for Swine Genetic Improvement and Germplasm Innovation, Ministry of Science and Technology of China, Jiangxi Agricultural University, Nanchang, 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