{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T08:37:04Z","timestamp":1778402224020,"version":"3.51.4"},"reference-count":169,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"63","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Immunol."],"published-print":{"date-parts":[[2021,9,24]]},"abstract":"<jats:p>SARS-CoV-2 evades immune recognition in humans but not bats, pointing to potential strategies for therapeutic intervention.<\/jats:p>","DOI":"10.1126\/sciimmunol.abd0205","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T17:55:25Z","timestamp":1631901325000},"source":"Crossref","is-referenced-by-count":34,"title":["Of bats and men: Immunomodulatory treatment options for COVID-19 guided by the immunopathology of SARS-CoV-2 infection"],"prefix":"10.1126","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0465-6018","authenticated-orcid":true,"given":"Michael J.","family":"Christie","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Monash University, Melbourne, Victoria 3168, Australia."},{"name":"Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria 3168, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0196-1570","authenticated-orcid":true,"given":"Aaron T.","family":"Irving","sequence":"additional","affiliation":[{"name":"Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China."},{"name":"Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining 314400, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4144-2537","authenticated-orcid":true,"given":"Samuel C.","family":"Forster","sequence":"additional","affiliation":[{"name":"Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Melbourne, Victoria, Australia."},{"name":"Department of Molecular and Translational Sciences, Monash University, Melbourne, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin J.","family":"Marsland","sequence":"additional","affiliation":[{"name":"Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4741-3035","authenticated-orcid":true,"given":"Philip M.","family":"Hansbro","sequence":"additional","affiliation":[{"name":"Centre for Inflammation, Centenary Institute, Sydney, NSW 2050, Australia."},{"name":"Centre for Inflammation, School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW 2007, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Hertzog","sequence":"additional","affiliation":[{"name":"Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Melbourne, Victoria, Australia."},{"name":"Department of Molecular and Translational Sciences, Monash University, Melbourne, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7439-3834","authenticated-orcid":true,"given":"Claudia A.","family":"Nold-Petry","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Monash University, Melbourne, Victoria 3168, Australia."},{"name":"Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria 3168, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9682-4618","authenticated-orcid":true,"given":"Marcel F.","family":"Nold","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Monash University, Melbourne, Victoria 3168, Australia."},{"name":"Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria 3168, Australia."},{"name":"Monash Newborn, Monash Children\u2019s Hospital, Melbourne, Victoria, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30251-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30484-9"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03426-1"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2021.26.28.2100573"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-020-00340-z"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.058"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab456"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","unstructured":"J. A. Lednicky M. S. Tagliamonte S. K. White M. A. Elbadry M. M. Alam C. J. Stephenson T. S. Bonny J. C. Loeb T. Telisma S. Chavannes D. A. Ostrov C. Mavian V. M. B. De Rochars M. Salemi J. G. Morris Emergence of porcine delta-coronavirus pathogenic infections among children in Haiti through independent zoonoses and convergent evolution. medRxiv 2021.2003.2019.21253391 [Preprint]. 25 March 2021. https:\/\/doi.org\/10.1101\/2021.03.19.21253391.","DOI":"10.1101\/2021.03.19.21253391"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2286-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd2985"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-021-00908-w"},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","unstructured":"F. A. Lempp L. Soriaga M. Montiel-Ruiz F. Benigni J. Noack Y.-J. Park S. Bianchi A. C. Walls J. E. Bowen J. Zhou H. Kaiser M. Agostini M. Meury E. Dellota Jr. S. Jaconi E. Cameroni H. W. Virgin A. Lanzavecchia D. Veesler L. Purcell A. Telenti D. Corti Membrane lectins enhance SARS-CoV-2 infection and influence the neutralizing activity of different classes of antibodies. bioRxiv 2021.04.03.438258 [Preprint]. 4 April 2021. https:\/\/doi.org\/10.1101\/2021.04.03.438258.","DOI":"10.1101\/2021.04.03.438258"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-01227-z"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.14003"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(20)30172-5"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2020.07.027"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","unstructured":"A. B. Freitas O. A. Cavalcanti L. P. de G\u00f3es Cavalcanti A. M. Siqueira D. B. de Castro C. F. da Costa D. R. Queir\u00f3z Lemos E. N. C. Barros The emergence of novel SARS-CoV-2 variant P.1 in Amazonas (Brazil) was temporally associated with a change in the age and gender profile of COVID-19 mortality. SciELO [Preprint]. 26 March 2021. https:\/\/doi.org\/10.1590\/SciELOPreprints.2030.","DOI":"10.2139\/ssrn.3804788"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2100362"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1513"},{"key":"e_1_3_2_22_2","unstructured":"WHO Tracking SARS-CoV-2 variants (2021); www.who.int\/en\/activities\/tracking-SARS-CoV-2-variants\/."},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.03.036"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30483-7"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2648"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2020-215337"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2009575"},{"key":"e_1_3_2_28_2","doi-asserted-by":"crossref","unstructured":"B. Li A. Deng K. Li Y. Hu Z. Li Q. Xiong Z. Liu Q. Guo L. Zou H. Zhang M. Zhang F. Ouyang J. Su W. Su J. Xu H. Lin J. Sun J. Peng H. Jiang P. Zhou T. Hu M. Luo Y. Zhang H. Zheng J. Xiao T. Liu R. Che H. Zeng Z. Zheng Y. Huang J. Yu L. Yi J. Wu J. Chen H. Zhong X. Deng M. Kang O. G. Pybus M. Hall K. A. Lythgoe Y. Li J. Yuan J. He J. Lu Viral infection and transmission in a large well-traced outbreak caused by the SARS-CoV-2 Delta variant. medRxiv 2021.2007.2007.21260122 [Preprint]. 23 July 2021. https:\/\/doi.org\/10.1101\/2021.07.07.21260122.","DOI":"10.1038\/s41467-022-28089-y"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab721"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30566-3"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.19719"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201012"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01283-z"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31129-6"},{"key":"e_1_3_2_35_2","unstructured":"AAP CHA (2021); https:\/\/services.aap.org\/en\/pages\/2019-novel-coronavirus-COVID-19-infections\/children-and-COVID-19-state-level-data-report\/."},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd4250"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.07.049"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00937-x"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S277716"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2021.e06187"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2022643118"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msaa094"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2017.01.014"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1000081"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201707"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-019-0181-7"},{"key":"e_1_3_2_47_2","doi-asserted-by":"crossref","unstructured":"H. Xu S. A. Chitre I. A. Akinyemi J. C. Loeb J. A. Lednicky M. T. McIntosh S. Bhaduri-McIntosh SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway. bioRxiv 2020.10.27.357731 [Preprint]. 27 October 2020. https:\/\/doi.org\/10.1101\/2020.10.27.357731.","DOI":"10.1101\/2020.10.27.357731"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-25015-6"},{"key":"e_1_3_2_49_2","doi-asserted-by":"crossref","first-page":"e108249","DOI":"10.15252\/embj.2021108249","article-title":"SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage","author":"Ma J.","year":"2021","unstructured":"J. Ma, F. Zhu, M. Zhao, F. Shao, D. Yu, J. Ma, X. Zhang, W. Li, Y. Qian, Y. Zhang, D. Jiang, S. Wang, P. Xia, SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J. e108249 (2021).","journal-title":"EMBO J."},{"key":"e_1_3_2_50_2","first-page":"211","article-title":"Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8\/SIGIRR","volume":"14","author":"Polentarutti N.","year":"2003","unstructured":"N. Polentarutti, G. P. Rol, M. Muzio, D. Bosisio, M. Camnasio, F. Riva, C. Zoja, A. Benigni, S. Tomasoni, A. Vecchi, C. Garlanda, A. Mantovani, Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8\/SIGIRR. Eur. Cytokine Netw. 14, 211\u2013218 (2003).","journal-title":"Eur. Cytokine Netw."},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.90443"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1944"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.39328"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc6261"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc6027"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.08.001"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21414-x"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abd6197"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.04.026"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0901-9"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.05.006"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3133"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.07.001"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.04.008"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-020-00731-9"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2588-y"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-00840-x"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108234"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd4570"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-03065-y"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd4585"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abd1554"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2020.04.017"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18854-2"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.580641"},{"key":"e_1_3_2_76_2","article-title":"SARS-CoV-2 nucleocapsid protein targets RIG-I-like receptor pathways to inhibit the induction of interferon response","volume":"10","author":"Oh S. J.","year":"2021","unstructured":"S. J. Oh, O. S. Shin, SARS-CoV-2 nucleocapsid protein targets RIG-I-like receptor pathways to inhibit the induction of interferon response. Cell 10, (2021).","journal-title":"Cell"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.700926"},{"key":"e_1_3_2_78_2","doi-asserted-by":"crossref","unstructured":"L. G. Thorne M. Bouhaddou A.-K. Reuschl L. Zuliani-Alvarez B. Polacco A. Pelin J. Batra M. V. X. Whelan M. Ummadi A. Rojc J. Turner K. Obernier H. Braberg M. Soucheray A. Richards K.-H. Chen B. Harjai D. Memon M. Hosmillo J. Hiatt A. Jahun I. G. Goodfellow J. M. Fabius K. Shokat N. Jura K. Verba M. Noursadeghi P. Beltrao D. L. Swaney A. Garcia-Sastre C. Jolly G. J. Towers N. J. Krogan Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant. bioRxiv 2021.2006.2006.446826 [Preprint]. 7 June 2021. https:\/\/doi.org\/10.1101\/2021.06.06.446826.","DOI":"10.1101\/2021.06.06.446826"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2024202118"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abg0833"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01753-18"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0063-8"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2020.04.007"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2010540117"},{"key":"e_1_3_2_85_2","doi-asserted-by":"crossref","unstructured":"T. Gao M. Hu X. Zhang H. Li L. Zhu H. Liu Q. Dong Z. Zhang Z. Wang Y. Hu Y. Fu Y. Jin K. Li S. Zhao Y. Xiao S. Luo L. Li L. Zhao J. Liu H. Zhao Y. Liu W. Yang J. Peng X. Chen P. Li Y. Liu Y. Xie J. Song L. Zhang Q. Ma X. Bian W. Chen X. Liu Q. Mao C. Cao Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation. medRxiv 2020.2003.2029.20041962 [Preprint]. 18 June 2020. https:\/\/doi.org\/10.1101\/2020.03.29.20041962.","DOI":"10.1101\/2020.03.29.20041962"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100590"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc8511"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2609.201495"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.06.024"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.09.038"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.12.002"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0762-x"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.08.025"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20642-x"},{"key":"e_1_3_2_95_2","doi-asserted-by":"crossref","unstructured":"L. B. Rodda J. Netland L. Shehata K. B. Pruner P. A. Morawski C. Thouvenel K. K. Takehara J. Eggenberger E. Hemann H. R. Waterman M. L. Fahning Y. Chen J. Rathe C. Stokes S. Wrenn B. Fiala L. Carter J. A. Hamerman N. P. King M. Gale Jr. D. J. Campbell D. Rawlings M. Pepper Functional SARS-CoV-2-specific immune memory persists after mild COVID-19. Res Sq [Preprint] (2020).","DOI":"10.1101\/2020.08.11.20171843"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf4063"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22036-z"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abg6916"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03207-w"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00559-7"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03777-9"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2108891"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00675-9"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2034545"},{"key":"e_1_3_2_105_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21336-8"},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1275"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abe3024"},{"key":"e_1_3_2_108_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature22975"},{"key":"e_1_3_2_109_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1118391"},{"key":"e_1_3_2_110_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vex012"},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2020.09.030"},{"key":"e_1_3_2_112_2","doi-asserted-by":"crossref","unstructured":"M. C. Wong S. J. Javornik Cregeen N. J. Ajami J. F. Petrosino Evidence of recombination in coronaviruses implicating pangolin origins of nCoV-2019. bioRxiv 2020.02.07.939207 [Preprint]. 13 February 2020. https:\/\/doi.org\/10.1101\/2020.02.07.939207.","DOI":"10.1101\/2020.02.07.939207"},{"key":"e_1_3_2_113_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-020-0771-4"},{"key":"e_1_3_2_114_2","doi-asserted-by":"crossref","unstructured":"S. Pollett M. A. Conte M. Sanborn R. G. Jarman G. M. Lidl K. Modjarrad I. M. Berry A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic. bioRxiv 2021.03.07.434287 [Preprint]. 8 March 2021. https:\/\/doi.org\/10.1101\/2021.03.07.434287.","DOI":"10.1101\/2021.03.07.434287"},{"key":"e_1_3_2_115_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa224"},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032713-120236"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-019-0371-3"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182866"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108345"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.01.006"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00435"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152135"},{"key":"e_1_3_2_123_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(20)30089-6"},{"key":"e_1_3_2_124_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1608.100208"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00245-17"},{"key":"e_1_3_2_126_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.070"},{"key":"e_1_3_2_127_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000436"},{"key":"e_1_3_2_128_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.0994"},{"key":"e_1_3_2_129_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1051-9"},{"key":"e_1_3_2_130_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25948"},{"key":"e_1_3_2_131_2","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.8.15.8001745"},{"key":"e_1_3_2_132_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001402"},{"key":"e_1_3_2_133_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03364-w"},{"key":"e_1_3_2_134_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab447"},{"key":"e_1_3_2_135_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2422-6"},{"key":"e_1_3_2_136_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199606273342603"},{"key":"e_1_3_2_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(20)30170-3"},{"key":"e_1_3_2_138_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-020-01367-z"},{"key":"e_1_3_2_139_2","doi-asserted-by":"crossref","unstructured":"B. K. Patterson H. Seethamraju K. Dhody M. J. Corley K. Kazempour J. P. Lalezari A. P. S. Pang C. Sugai E. B. Francisco A. Pise H. Rodrigues M. Ryou H. L. Wu G. M. Webb B. S. Park S. Kelly N. Pourhassan A. Lelic L. Kdouh M. Herrera E. Hall E. Aklin L. Ndhlovu J. B. Sacha Disruption of the CCL5\/RANTES-CCR5 pathway restores immune homeostasis and reduces plasma viral load in critical COVID-19. medRxiv 2020.05.02.20084673 [Preprint]. 5 May 2020. https:\/\/doi.org\/10.1101\/2020.05.02.20084673.","DOI":"10.1101\/2020.05.02.20084673"},{"key":"e_1_3_2_140_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2023184"},{"key":"e_1_3_2_141_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30511-7"},{"key":"e_1_3_2_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2020.07.005"},{"key":"e_1_3_2_143_2","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202012465"},{"key":"e_1_3_2_144_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2031994"},{"key":"e_1_3_2_145_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2101643"},{"key":"e_1_3_2_146_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2020.05.002"},{"key":"e_1_3_2_147_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201706-1172OC"},{"key":"e_1_3_2_148_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1443"},{"key":"e_1_3_2_149_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.03.062"},{"key":"e_1_3_2_150_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"e_1_3_2_151_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.17023"},{"key":"e_1_3_2_152_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01009-2020"},{"key":"e_1_3_2_153_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.590598"},{"key":"e_1_3_2_154_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf7945"},{"key":"e_1_3_2_155_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2423-5"},{"key":"e_1_3_2_156_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2007764"},{"key":"e_1_3_2_157_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.16349"},{"key":"e_1_3_2_158_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31022-9"},{"key":"e_1_3_2_159_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abf1906"},{"key":"e_1_3_2_160_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2035002"},{"key":"e_1_3_2_161_2","unstructured":"NIH National Institutes of Health (2021); www.covid19treatmentguidelines.nih.gov."},{"key":"e_1_3_2_162_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abi9007"},{"key":"e_1_3_2_163_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abi9002"},{"key":"e_1_3_2_164_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025385"},{"key":"e_1_3_2_165_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2015.0576"},{"key":"e_1_3_2_166_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2003352117"},{"key":"e_1_3_2_167_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1230835"},{"key":"e_1_3_2_168_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1814995116"},{"key":"e_1_3_2_169_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1916414117"},{"key":"e_1_3_2_170_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-018-0950-6"}],"container-title":["Science Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/sciimmunol.abd0205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T12:58:17Z","timestamp":1705409897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/sciimmunol.abd0205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,24]]},"references-count":169,"journal-issue":{"issue":"63","published-print":{"date-parts":[[2021,9,24]]}},"alternative-id":["10.1126\/sciimmunol.abd0205"],"URL":"https:\/\/doi.org\/10.1126\/sciimmunol.abd0205","relation":{},"ISSN":["2470-9468"],"issn-type":[{"value":"2470-9468","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,24]]},"article-number":"eabd0205"}}