{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:11:21Z","timestamp":1791223881989,"version":"4.1.0"},"reference-count":58,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"362","license":[{"start":{"date-parts":[[2016,2,3]],"date-time":"2016-02-03T00:00:00Z","timestamp":1454457600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01 HL116581"],"award-info":[{"award-number":["R01 HL116581"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Signal."],"published-print":{"date-parts":[[2015,2,3]]},"abstract":"<jats:p>Proteins in the Hippo pathway regulate Raf-mediated cardiac hypertrophy in flies.<\/jats:p>","DOI":"10.1126\/scisignal.2005719","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T15:22:51Z","timestamp":1422976971000},"source":"Crossref","is-referenced-by-count":34,"title":["Cardiac hypertrophy induced by active Raf depends on Yorkie-mediated transcription"],"prefix":"10.1126","volume":"8","author":[{"given":"Lin","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Daniels","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","unstructured":"E. Braunwald R. O. Bonow Braunwald\u2019s Heart Disease: A Textbook of Cardiovascular Medicine (Elsevier\/Saunders Philadelphia PA ed. 9 2012)."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1983"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng2073"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI44929"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2011.01.001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.007864"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2012.06.012"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02091"},{"key":"e_1_3_2_10_2","first-page":"964","article-title":"Raf-mediated cardiac hypertrophy in adult Drosophila","volume":"6","author":"Yu L.","year":"2013","unstructured":"Yu L., Daniels J., Glaser A. E., Wolf M. J., Raf-mediated cardiac hypertrophy in adult Drosophila. Dis. Model. Mech. 6, 964\u2013976 (2013).","journal-title":"Dis. Model. Mech."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.07.019"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.06.007"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2013.04.021"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.034"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.12.043"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1602907"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00824-3"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00549-X"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.43"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2009.10.046"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2008.01.007"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2008.01.006"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1664408"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1199010"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1116136109"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2002278"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2013.01.020"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.4161\/cc.4.3.1531"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103233"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(01)00361-6"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507359103"},{"key":"e_1_3_2_32_2","unstructured":"L. Yu J. P. Daniels M. F. Wolf Manual of Research Techniques in Cardiovascular Medicine H. Ardehali R. Bolli D. W. Losordo Eds. (Wiley Blackwell Chichester West Sussex UK 2014) pp. 432\u2013439."},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81385-9"},{"key":"e_1_3_2_34_2","first-page":"4570","article-title":"Antibodies to proliferating cell nuclear antigen as S-phase probes in flow cytometric cell cycle analysis","volume":"51","author":"Landberg G.","year":"1991","unstructured":"Landberg G., Roos G., Antibodies to proliferating cell nuclear antigen as S-phase probes in flow cytometric cell cycle analysis. Cancer Res. 51, 4570\u20134574 (1991).","journal-title":"Cancer Res."},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005942"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2828(86)80981-6"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10147"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/202100a0"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.12.002"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1820009"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022278"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002632"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.15.8.4125"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.08.082"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.09.011"},{"key":"e_1_3_2_46_2","first-page":"2839","article-title":"Cellular proteins homologous to the viral yes gene product","volume":"6","author":"Sudol M.","year":"1986","unstructured":"Sudol M., Hanafusa H., Cellular proteins homologous to the viral yes gene product. Mol. Cell. Biol. 6, 2839\u20132846 (1986).","journal-title":"Mol. Cell. Biol."},{"key":"e_1_3_2_47_2","first-page":"1629","article-title":"Expression of cellular-yes protein in mammalian tissues","volume":"5","author":"Zhao Y. H.","year":"1990","unstructured":"Zhao Y. H., Krueger J. G., Sudol M., Expression of cellular-yes protein in mammalian tissues. Oncogene 5, 1629\u20131635 (1990).","journal-title":"Oncogene"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2006.10.060"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.103080cf"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.23788"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M400154200"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2014.01.010"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2014.10"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000969"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.118.2.401"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007132"},{"key":"e_1_3_2_57_2","unstructured":"M. Ashburner K. G. Golic R. S. Hawley Drosophila: A Laboratory Handbook (Cold Spring Harbor Laboratory Press Cold Spring Harbor NY ed. 2 2005)."},{"key":"e_1_3_2_58_2","first-page":"1423","article-title":"Fluorescent labeling of Drosophila heart structures","volume":"13","author":"Alayari N. N.","year":"2009","unstructured":"Alayari N. N., Vogler G., Taghli-Lamallem O., Ocorr K., Bodmer R., Cammarato A., Fluorescent labeling of Drosophila heart structures. J. Vis. Exp. 13, 1423 (2009).","journal-title":"J. Vis. Exp."},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1952710"}],"container-title":["Science Signaling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scisignal.2005719","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T06:21:12Z","timestamp":1705386072000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scisignal.2005719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,3]]},"references-count":58,"journal-issue":{"issue":"362","published-print":{"date-parts":[[2015,2,3]]}},"alternative-id":["10.1126\/scisignal.2005719"],"URL":"https:\/\/doi.org\/10.1126\/scisignal.2005719","relation":{},"ISSN":["1945-0877","1937-9145"],"issn-type":[{"value":"1945-0877","type":"print"},{"value":"1937-9145","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,3]]}}}