{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T16:39:39Z","timestamp":1793205579995,"version":"4.5.0"},"reference-count":58,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"219","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2014,1,15]]},"abstract":"<jats:p>Negatively charged immune-modifying microparticles bind to the scavenger receptor MARCO on inflammatory monocytes, resulting in their apoptosis and reduced inflammatory damage in a range of diseases.<\/jats:p>","DOI":"10.1126\/scitranslmed.3007563","type":"journal-article","created":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T14:25:01Z","timestamp":1389795901000},"source":"Crossref","is-referenced-by-count":327,"title":["Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles"],"prefix":"10.1126","volume":"6","author":[{"given":"Daniel R.","family":"Getts","sequence":"first","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."},{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."},{"name":"Cour Pharmaceutical Development Company, Elmhurst, IL 60126, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael L.","family":"Terry","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."},{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghann Teague","family":"Getts","sequence":"additional","affiliation":[{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine","family":"Deffrasnes","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Neurology, Universit\u00e4tsklinikum Bonn, Bonn 53113, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caryn","family":"van Vreden","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Ashhurst","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belal","family":"Chami","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiling","family":"Wu","sequence":"additional","affiliation":[{"name":"Collaborative Transplant Research Group, Renal Medicine, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Ma","sequence":"additional","affiliation":[{"name":"Collaborative Transplant Research Group, Renal Medicine, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Martin","sequence":"additional","affiliation":[{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lonnie D.","family":"Shae","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Witting","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey S.","family":"Kansas","sequence":"additional","affiliation":[{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"University Hospital M\u00fcnster, Institute of Medical Microbiology\u2014Clinical Virology, Interdisciplinary Center of Clinical Research, M\u00fcnster 48419, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wali","family":"Hafezi","sequence":"additional","affiliation":[{"name":"University Hospital M\u00fcnster, Institute of Medical Microbiology\u2014Clinical Virology, Interdisciplinary Center of Clinical Research, M\u00fcnster 48419, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain L.","family":"Campbell","sequence":"additional","affiliation":[{"name":"School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Reilly","sequence":"additional","affiliation":[{"name":"The School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Say","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biomolecular Science, Macquarie University, Sydney, New South Wales 2109, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biomolecular Science, Macquarie University, Sydney, New South Wales 2109, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie Y.","family":"White","sequence":"additional","affiliation":[{"name":"School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart J.","family":"Cordwell","sequence":"additional","affiliation":[{"name":"School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Chadban","sequence":"additional","affiliation":[{"name":"Collaborative Transplant Research Group, Renal Medicine, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward B.","family":"Thorp","sequence":"additional","affiliation":[{"name":"Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shisan","family":"Bao","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen D.","family":"Miller","sequence":"additional","affiliation":[{"name":"Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J. C.","family":"King","sequence":"additional","affiliation":[{"name":"The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.89"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080421"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-168575"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1001002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.05.010"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42304"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1003844"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.111.960385"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI28549"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1175202"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-246"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2010.12.004"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-235028"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011049"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200105)44:5<1022::AID-ANR181>3.0.CO;2-N"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI62636"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.916346"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1989"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.330.6008.1163"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2011.575359"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2010.08.001"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2011.04244.x"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1229568"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2007.04798.x"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M110.006353"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(97)00133-6"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2009.1045"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1006\/taap.2001.9190"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/bc200685a"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-9574LSF"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29919"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/nn400769e"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2434"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1004175"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfm050"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.3.1148"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202113"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.04.008"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111913"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)89189-X"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-10-313239"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni1430"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20111009"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.061986"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-383-1_9"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2008.310"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M605229200"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.9.6058"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4400786"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.9.5912"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29968"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-009-0813-5"},{"key":"e_1_3_2_54_2","first-page":"144","article-title":"Natalizumab and progressive multifocal leukoencephalopathy: Highlights of the International Workshop on JC Virus\/PML and Multiple Sclerosis, June 3-4, 2005, Philadelphia PA.","volume":"2","author":"Tyler K. L.","year":"2005","unstructured":"Tyler K. L., Khalili K., Natalizumab and progressive multifocal leukoencephalopathy: Highlights of the International Workshop on JC Virus\/PML and Multiple Sclerosis, June 3-4, 2005, Philadelphia PA. Rev. Neurol. Dis. 2, 144\u2013149 (2005).","journal-title":"Rev. Neurol. Dis."},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2011.4"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31008"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008020170"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009101048"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr2006928"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.3007563","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T12:51:39Z","timestamp":1705409499000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.3007563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,15]]},"references-count":58,"journal-issue":{"issue":"219","published-print":{"date-parts":[[2014,1,15]]}},"alternative-id":["10.1126\/scitranslmed.3007563"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.3007563","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,15]]}}}